PDB entry 4oq6
View 4oq6 on RCSB PDB site
Description: Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid
Class: apoptosis/inhibitor
Keywords: APOPTOSIS-INHIBITOR complex
Deposited on
2014-02-07, released
2014-03-12
The last revision prior to the SCOPe 2.03 freeze date was dated
2014-03-12, with a file datestamp of
2014-03-07.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: 0.203
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
Species: Homo sapiens [TaxId:9606]
Gene: MCL1, BCL2L3
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
Species: Homo sapiens [TaxId:9606]
Gene: MCL1, BCL2L3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4oq6b_ - Heterogens: 2UV, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4oq6B (B:)
gsmdlyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedleg
Sequence, based on observed residues (ATOM records): (download)
>4oq6B (B:)
dlyrqsleiisrylreqatgakgatsrkaletlrrvgdgvqrnhetafqgmlrkldikne
ddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitdvlvr
tkrdwlvkqrgwdgfveffhv