PDB entry 4opr

View 4opr on RCSB PDB site
Description: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation
Class: hydrolase
Keywords: Beta-lactamase, HYDROLASE
Deposited on 2014-02-06, released 2015-05-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TEM-94 ES-beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: bla-TEM-94
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8KMX3 (0-262)
      • engineered mutation (16)
      • engineered mutation (26)
      • engineered mutation (78)
      • engineered mutation (94)
      • engineered mutation (158)
      • engineered mutation (175)
    Domains in SCOPe 2.08: d4opra_
  • Heterogens: CA, PG4, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4oprA (A:)
    hpetlvkvkdaedqlggrvgyieldlasgkilesfrpeerfpmmstfkvllcgavlsrvd
    agqeqlgrrihysqndlveyspvtekhltdgmtvgelcsaaitmsdntaanlllttiggp
    keltaflhnmgdhvtrldrwepelneaipnderdtttpvamattlrklltgelltaasrq
    qlidwmeadkvagpllrsalpagwfiadksgasergsrgiiaalgpdgkpsrivviymtg
    sqatmdernrqiaeigaslikhw