PDB entry 4ooy

View 4ooy on RCSB PDB site
Description: Avibactam and class C beta-lactamases: mechanism of inhibition, conservation of binding pocket and implications for resistance
Class: hydrolase/hydrolase inhibitor
Keywords: B-lactamase, Carbamoylation with the inhibitor, hydrolase-hydrolase inhibitor complex
Deposited on 2014-02-04, released 2014-08-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-14, with a file datestamp of 2018-02-09.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Pseudomonas aeruginosa [TaxId:208964]
    Gene: ampC, PA4110
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ooya_
  • Heterogens: NXL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4ooyA (A:)
apadrlkalvdaavqpvmkandipglavaislkgephyfsyglaskedgrrvtpetlfei
gsvsktftatlagyaltqdkmrlddrasqhwpalqgsrfdgislldlatytagglplqfp
dsvqkdqaqirdyyrqwqptyapgsqrlysnpsiglfgylaarslgqpferlmeqqvfpa
lgleqthldvpeaalaqyaqgygkddrplrvgpgpldaegygvktsaadllrfvdanlhp
erldrpwaqaldathrgyykvgdmtqglgweaydwpislkrlqagnstpmalqphriarl
papqalegqrllnktgstngfgayvafvpgrdlglvilanrnypnaervkiayailsgl