PDB entry 4omo

View 4omo on RCSB PDB site
Description: Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E
Class: transferase
Keywords: beta-barrel sandwich, kinase, proline rich motifs, TRANSFERASE
Deposited on 2014-01-27, released 2014-12-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-12-17, with a file datestamp of 2014-12-12.
Experiment type: XRAY
Resolution: 1.04 Å
R-factor: 0.149
AEROSPACI score: 0.88 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (4-60)
      • expression tag (0-3)
      • engineered mutation (47)
    Domains in SCOPe 2.05: d4omoa_
  • Chain 'B':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (4-End)
      • expression tag (0-3)
      • engineered mutation (47)
    Domains in SCOPe 2.05: d4omob_
  • Heterogens: NI, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4omoA (A:)
    gshmtfvalydyesrtetdlsfkkgerlqivnntegdwwlahslttgetgyipsnyvaps
    d
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4omoB (B:)
    gshmtfvalydyesrtetdlsfkkgerlqivnntegdwwlahslttgetgyipsnyvaps
    d
    

    Sequence, based on observed residues (ATOM records): (download)
    >4omoB (B:)
    gshmtfvalydyesrtetdlsfkkgerlqivntegdwwlahslttgetgyipsnyvaps