PDB entry 4olc

View 4olc on RCSB PDB site
Description: Carbamate kinase from Giardia lamblia thiocarbamoylated by disulfiram on Cys242
Class: transferase
Keywords: ADP, Mg2+, carbamate, carbamoyl phosphate, TRANSFERASE
Deposited on 2014-01-23, released 2014-02-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-04-30, with a file datestamp of 2014-04-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.206
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carbamate kinase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_16453
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4olca_
  • Chain 'B':
    Compound: carbamate kinase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_16453
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4olcb_
  • Chain 'C':
    Compound: carbamate kinase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_16453
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4olcc_
  • Chain 'D':
    Compound: carbamate kinase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_16453
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4olcd_
  • Heterogens: CIT, DCD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4olcA (A:)
gmsagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqv
gaiklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlv
dpkdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygv
iktlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvl
nacinykkpderkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitsls
tavdalngkcgtriikd

    Sequence, based on observed residues (ATOM records): (download) 
    >4olcA (A:)
sagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqvga
iklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlvdp
kdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygvik
tlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvlna
cirkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitslstavdalngk
cgtriikd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4olcB (B:)
gmsagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqv
gaiklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlv
dpkdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygv
iktlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvl
nacinykkpderkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitsls
tavdalngkcgtriikd

    Sequence, based on observed residues (ATOM records): (download) 
    >4olcB (B:)
sagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqvga
iklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlvdp
kdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygvik
tlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvlna
cirkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitslstavdalngk
cgtriikd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4olcC (C:)
gmsagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqv
gaiklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlv
dpkdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygv
iktlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvl
nacinykkpderkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitsls
tavdalngkcgtriikd

    Sequence, based on observed residues (ATOM records): (download) 
    >4olcC (C:)
sagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqvga
iklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlvdp
kdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygvik
tlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvlna
cirkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitslstavdalngk
cgtriikd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4olcD (D:)
gmsagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqv
gaiklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlv
dpkdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygv
iktlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvl
nacinykkpderkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitsls
tavdalngkcgtriikd

    Sequence, based on observed residues (ATOM records): (download) 
    >4olcD (D:)
sagktvvialggnamlqakekgdydtqrknveiaaseiykihkagykvvltsgngpqvga
iklqnqaaagvspemplhvcgamsqgfigymmsqamdnvfcannepancvtcvtqtlvdp
kdqaftnptkpvgrfyteqeakdlmaanpgkilredagrgwrvvvpsprpleiveygvik
tlidnnvlvictngggipckrenkvisgvdavidkdlatsllaktlnsdylmiltdvlna
cirkleeiklseilalekdghfaagsmgpkvraaieftqatgkmsiitslstavdalngk
cgtriikd