PDB entry 4okx

View 4okx on RCSB PDB site
Description: Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Class: hormone receptor/peptide
Keywords: Alpha-helix, Hormone/growth Factor Receptor, Phosphorylation, HORMONE RECEPTOR-PEPTIDE complex, signal transduction
Deposited on 2014-01-23, released 2014-08-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.199
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10275
      • engineered mutation (71)
      • engineered mutation (90)
    Domains in SCOPe 2.08: d4okxa_
  • Chain 'B':
    Compound: co-regulator peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 4OKX
  • Heterogens: SO4, 198, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4okxA (A:)
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyslmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfhtq

    Sequence, based on observed residues (ATOM records): (download) 
    >4okxA (A:)
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyslmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiacsrrfyq
ltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyfht

  • Chain 'B':
    No sequence available.