SCOPe 2.05: Structural Classification of Proteins

PDB entry 4okn

View 4okn on RCSB PDB site
Description: Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate
Class: oxidoreductase/antibiotic
Keywords: Rossmann Fold, NADH/NAD+ cofactor, OXIDOREDUCTASE-ANTIBIOTIC complex
Deposited on 2014-01-22, released 2014-12-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-12-03, with a file datestamp of 2014-11-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.208
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4okna1, d4okna2
Chain 'B':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4oknb1, d4oknb2
Chain 'C':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4oknc1, d4oknc2
Chain 'D':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4oknd1, d4oknd2
Chain 'E':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4okne1, d4okne2
Chain 'F':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4oknf1, d4oknf2
Chain 'G':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4okng1, d4okng2
Chain 'H':
Compound: L-lactate dehydrogenase A chain
Species: Homo sapiens [TaxId:9606]
Gene: LDHA, PIG19
Database cross-references and differences (RAF-indexed):
- Uniprot P00338 (0-330)
Domains in SCOPe 2.05: d4oknh1, d4oknh2
Heterogens: NAI, OXL, SO4, KAN, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4oknA (A:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqfhhhhhh