PDB entry 4okh

View 4okh on RCSB PDB site
Description: Crystal structure of calpain-3 penta-EF-hand domain
Class: hydrolase
Keywords: calcium-binding, EF-hand, Hydrolase
Deposited on 2014-01-22, released 2014-05-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calpain-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CAN3, CANP3, CANPL3, CAPN3, NCL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20807 (Start-180)
      • expression tag (181-185)
    Domains in SCOPe 2.08: d4okha1, d4okha2
  • Chain 'B':
    Compound: Calpain-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CAN3, CANP3, CANPL3, CAPN3, NCL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20807 (Start-180)
      • expression tag (181)
    Domains in SCOPe 2.08: d4okhb1, d4okhb2
  • Chain 'C':
    Compound: Calpain-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CAN3, CANP3, CANPL3, CAPN3, NCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4okhc_
  • Heterogens: CA, PEU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4okhA (A:)
mgssdqeseeqqqfrnifkqiagddmeicadelkkvlntvvnkhkdlkthgftlescrsm
ialmdtdgsgklnlqefhhlwnkikawqkifkhydtdqsgtinsyemrnavndagfhlnn
qlydiitmryadkhmnidfdsficcfvrlegmfrafhafdkdgdgiiklnvlewlqltmy
alehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4okhA (A:)
qqqfrnifkqiagddmeicadelkkvlntvvnkthgftlescrsmialmdtdgsgklnlq
efhhlwnkikawqkifkhydtdqsgtinsyemrnavndagfhlnnqlydiitmryadkhm
nidfdsficcfvrlegmfrafhafdkdgdgiiklnvlewlqltmyalehhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4okhB (B:)
mgssdqeseeqqqfrnifkqiagddmeicadelkkvlntvvnkhkdlkthgftlescrsm
ialmdtdgsgklnlqefhhlwnkikawqkifkhydtdqsgtinsyemrnavndagfhlnn
qlydiitmryadkhmnidfdsficcfvrlegmfrafhafdkdgdgiiklnvlewlqltmy
alehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4okhB (B:)
eseeqqqfrnifkqiagddmeicadelkkvlntvvnthgftlescrsmialmdtdgsgkl
nlqefhhlwnkikawqkifkhydtdqsgtinsyemrnavndagfhlnnqlydiitmryad
khmnidfdsficcfvrlegmfrafhafdkdgdgiiklnvlewlqltmyal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4okhC (C:)
mgssdqeseeqqqfrnifkqiagddmeicadelkkvlntvvnkhkdlkthgftlescrsm
ialmdtdgsgklnlqefhhlwnkikawqkifkhydtdqsgtinsyemrnavndagfhlnn
qlydiitmryadkhmnidfdsficcfvrlegmfrafhafdkdgdgiiklnvlewlqltmy
alehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4okhC (C:)
dmeicadelkkvlntvvhgftlescrsmialmdtdgsgklnlqefhhlwnkikawqkifk
hydtdqsgtinsyemrnavndagfhlnnqlydiitmryadkhmnidfdsficcfvrlegm
frafhafdkdgdgiiklnvlewlqltm