PDB entry 4ojq

View 4ojq on RCSB PDB site
Description: Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Fragment 1 [(5-bromo-1H-indol-3-yl)acetic acid]
Class: Hydrolase/Hydrolase Inhibitor
Keywords: HEPATITIS, ATPase, NTPase, NS3 Helicase, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2014-01-21, released 2014-03-05
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-04-02, with a file datestamp of 2014-03-28.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.22
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine protease NS3
    Species: Hepatitis C virus [TaxId:11103]
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot K4KA16 (Start-463)
      • conflict (338)
    Domains in SCOPe 2.05: d4ojqa1, d4ojqa2
  • Chain 'B':
    Compound: Serine protease NS3
    Species: Hepatitis C virus [TaxId:11103]
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot K4KA16
      • conflict (236)
      • conflict (338)
    Domains in SCOPe 2.05: d4ojqb1, d4ojqb2
  • Heterogens: 2SX, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ojqA (A:)
mgsshhhhhhssgrspvftdnssppavpqsfqvahlhaptgsgkstkvpaayaaqgykvl
vlnpsvaatlgfgaymskahgvdpnirtgvrtittgspitystygkfladggcsggaydi
iicdechstdatsilgigtvldqaetagarlvvlatatppgsvtvshpnieevalsttge
ipfygkaiplevikggrhlifchskkkcdelaaklvalginavayyrgldvsviptngdv
vvvstdalmtgftgdfdsvidcntcvtqtvdfsldptftietttlpqdavsrtqrrgrtg
rgkpgiyrfvapgerpsgmfdssvlcecydagcawyelmpaettvrlraymntpglpvcq
dhlefwegvftglthidahflsqtkqsgenfpylvayqatvcaraqapppswdqmwkcli
rlkptlhgptpllyrlgavqnevtlthpitkyimtcmsadlevv

    Sequence, based on observed residues (ATOM records): (download) 
    >4ojqA (A:)
dnssppavpqsfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymska
hgvdpnirtgvrtittgspitystygkfladggcsggaydiiicdechstdatsilgigt
vldqaetagarlvvlatatppgsvtvshpnieevalsttgeipfygkaiplevikggrhl
ifchskkkcdelaaklvalginavayyldvsvipdvvvvstdalmtgftgdfdsvidcnt
cvtqtvdfsldptftietttlpqdavsrtqrrgrtgrgkpgiyrfvapgerpsgmfdssv
lcecydagcawyelmpaettvrlraymntpglpvcqdhlefwegvftglthidahflsqt
kqsgenfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevt
lthpitkyimtcmsadlevv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ojqB (B:)
mgsshhhhhhssgrspvftdnssppavpqsfqvahlhaptgsgkstkvpaayaaqgykvl
vlnpsvaatlgfgaymskahgvdpnirtgvrtittgspitystygkfladggcsggaydi
iicdechstdatsilgigtvldqaetagarlvvlatatppgsvtvshpnieevalsttge
ipfygkaiplevikggrhlifchskkkcdelaaklvalginavayyrgldvsviptngdv
vvvstdalmtgftgdfdsvidcntcvtqtvdfsldptftietttlpqdavsrtqrrgrtg
rgkpgiyrfvapgerpsgmfdssvlcecydagcawyelmpaettvrlraymntpglpvcq
dhlefwegvftglthidahflsqtkqsgenfpylvayqatvcaraqapppswdqmwkcli
rlkptlhgptpllyrlgavqnevtlthpitkyimtcmsadlevv

    Sequence, based on observed residues (ATOM records): (download) 
    >4ojqB (B:)
nssppavpqsfqvahlhapttkvpaayaaqgykvlvlnpsvaatlgfgaymskahspity
stygkfladggcsggaydiiicdechstdatsilgigtvldqaetagarlvvlatatppg
svtvshpnieevalsttgeipfygkaiplevikggrhlifchskkkcdelaaklvalgin
avayyrgldvsviptngdvvvvstdalmgftgdfdsvidcntcvtqtvdfsldptftiet
ttlpqdavsrtqrrgrtgrgkpgiyrfvapgerpsgmfdssvlcecydagcawyelmpae
ttvrlraymntpglpvcqdhlefwegvftglthidahflsqtkqsgenfpylvayqatvc
araqapppswdqmwkclirlkptlhgptpllyrlgavqnevtlthpitkyimtcmsadle