PDB entry 4ogj
View 4ogj on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor TG-101348
Class: transcription/inhibitor
Keywords: bromodomain, bromodomain containing protein 4, JAK2 kinase inhibitor, FLT3 kinase inhibitor, structural genomics, Structural Genomics Consortium, SGC, TRANSCRIPTION-INHIBITOR complex
Deposited on
2014-01-16, released
2014-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-12, with a file datestamp of
2020-02-07.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ogja1, d4ogja2 - Chain 'B':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ogjb1, d4ogjb2 - Heterogens: EDO, 2TA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4ogjA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4ogjB (B:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee