PDB entry 4ogh

View 4ogh on RCSB PDB site
Description: Crystal structure of T877A-AR-LBD
Class: hormone receptor
Keywords: alpha helix, signal transduction, co-regulator, Phosphorylation, HORMONE RECEPTOR
Deposited on 2014-01-16, released 2014-08-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: 0.165
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10275 (Start-249)
      • engineered mutation (90)
      • engineered mutation (207)
    Domains in SCOPe 2.08: d4ogha_
  • Heterogens: HFT, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4oghA (A:)
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfhtq

    Sequence, based on observed residues (ATOM records): (download) 
    >4oghA (A:)
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsamlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiascsrrfy
qltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyfh
tq