PDB entry 4ogc

View 4ogc on RCSB PDB site
Description: Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Class: Hydrolase
Keywords: CRISPR-Cas, Cas9, HNH, RuvC, RNA-guided DNA endonuclease, cytoplasmic, Hydrolase
Deposited on 2014-01-15, released 2014-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.196
AEROSPACI score: -1.78 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HNH endonuclease domain protein
    Species: Actinomyces naeslundii [TaxId:1115803]
    Gene: HMPREF1129_2620
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ogca1, d4ogca2, d4ogca3, d4ogca4
  • Heterogens: ZN, MN, MG, SPD, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ogcA (A:)
mwyaslmsahhlrvgidvgthsvglatlrvddhgtpiellsalshihdsgvgkegkkdhd
trkklsgiarrarrllhhrrtqlqqldevlrdlgfpiptpgefldlneqtdpyrvwrvra
rlveeklpeelrgpaismavrhiarhrgwrnpyskvesllspaeespfmkalrerilatt
gevlddgitpgqamaqvalthnismrgpegilgklhqsdnaneirkicarqgvspdvckq
llravfkadsprgsavsrvapdplpgqgsfrrapkcdpefqrfriisivanlrisetkge
nrpltaderrhvvtfltedsqadltwvdvaeklgvhrrdlrgtavhtddgersaarppid
atdrimrqtkisslktwweeadseqrgamirylyedptdsecaeiiaelpeedqakldsl
hlpagraaysresltalsdhmlattddlhearkrlfgvddswappaeainapvgnpsvdr
tlkivgrylsavesmwgtpevihvehvrdgftsermaderdkanrrryndnqeamkkiqr
dygkegyisrgdivrldalelqgcaclycgttigyhtcqldhivpqagpgsnnrrgnlva
vcercnrsksntpfavwaqkcgiphvgvkeaigrvrgwrkqtpntssedltrlkkeviar
lrrtqedpeidersmesvawmanelhhriaaaypettvmvyrgsitaaarkaagidsrin
ligekgrkdridrrhhavdasvvalmeasvaktlaersslrgeqrltgkeqtwkqytgst
vgarehfemwrghmlhltelfnerlaedkvyvtqnirlrlsdgnahtvnpsklvshrlgd
gltvqqidractpalwcaltrekdfdeknglparedrairvhgheikssdyiqvfskrkk
tdsdrdetpfgaiavrggfveigpsihhariyrvegkkpvyamlrvfthdllsqrhgdlf
savippqsismrcaepklrkaittgnatylgwvvvgdeleinvdsftkyaigrfledfpn
ttrwricgydtnskltlkpivlaaeglenpssavneivelkgwrvainvltkvhptvvrr
dalgrpryssrsnlptswtie

    Sequence, based on observed residues (ATOM records): (download) 
    >4ogcA (A:)
sahhlrvgidvgthsvglatlrvddhgtpiellsalshihdsgsavsrvapdplpgqgsf
rrapkcdpefqrfriisivanlrisetkgenrpltaderrhvvtfltedsqadltwvdva
eklgvhrrdlrgtrsaarppidatdrimrqtkisslktwweeadseqrgamirylyedpt
dsecaeiiaelpeedqakldslhlpagraaysresltalsdhmlattddlhearkrlfgv
ddswappaeainapvgnpsvdrtlkivgrylsavesmwgtpevihvehvrdgftsermad
erdkanrrryndnqeamkkiqrdygkegyisrgdivrldalelqgcaclycgttigyhtc
qldhivpqagpgsnnrrgnlvavcercnrsksntpfavwaqkcgiphvgvkeaigrvrgw
rkqtpntssedltrlkkeviarlrrtqedpeidersmesvawmanelhhriaaaypettv
mvyrgsitaaarkaagidsrinligekgrkdridrrhhavdasvvalmeasvaktlaers
slrgeqrltgkeqtwkqytgstvgarehfemwrghmlhltelfnerlaedkvyvtqnirl
rlsdgnahtvnpsklvshrlgdgltvqqidractpalwcaltrekdfdeknglparedra
irvhgheikssdyiqvfskrkktdsdrdetpfgaiavrggfveigpsihhariyrvegkk
pvyamlrvfthdllsqrhgdlfsavippqsismrcaepklrkaittgnatylgwvvvgde
leinvdsftkyaigrfledfpnttrwricgydtnskltlkpivlaaeglenpssavneiv
elkgwrvainvltkvhptvvrrdalgrpryssrsnlptswtie