PDB entry 4ocw

View 4ocw on RCSB PDB site
Description: Crystal structure of human Fab CAP256-VRC26.06, a potent V1V2-directed HIV-1 neutralizing antibody
Class: immune system
Keywords: Fab, HIV-1, V1V2, CAP256, VRC26, IMMUNE SYSTEM
Deposited on 2014-01-09, released 2014-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-05-14, with a file datestamp of 2014-05-09.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.195
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: CAP256-VRC26.06 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4OCW (0-End)
    Domains in SCOPe 2.08: d4ocwh1, d4ocwh2
  • Chain 'L':
    Compound: CAP256-VRC26.06 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4OCW (0-End)
    Domains in SCOPe 2.08: d4ocwl_

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4ocwH (H:)
evqliesgggvvqpgrslrlscgasgfsfnnygmhwvrqapgkglewvagisfagikkyy
gtsvkgrftisrdnsknnfylqmnslrvedtalyycardlreleceewtlynyydfgsrg
pcvdprgvagsfdvwgqgtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpe
pvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvd
kkvepkscdkglevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4ocwH (H:)
evqliesgggvvqpgrslrlscgasgfsfnnygmhwvrqapgkglewvagisfagikkyy
gtsvkgrftisrdnsknnfylqmnslrvedtalyycardlreleceewtlynyydrgpcv
dprgvagsfdvwgqgtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvt
vswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
epkscdkglevlf

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4ocwL (L:)
qsvltqppsvsaapgqkvtiscsgstskigqnsvswyqqlpgtapklliyendrrpsgtp
drfsgsksgtsatlaitglqtgdeaeyycetwdgsggvfgtgtkvtvlgqpkanptvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4ocwL (L:)
qsvltqppsvsaapgqkvtiscsgstskigqnsvswyqqlpgtapklliyendrrpsgtp
drfsgsksgtsatlaitglqtgdeaeyycetwdgsggvfgtgtkvtvlgqpkanptvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvapt