PDB entry 4oct

View 4oct on RCSB PDB site
Description: Crystal structure of human ALKBH5 crystallized in the presence of Mn^{2+} and 2-oxoglutarate
Deposited on 2014-01-09, released 2014-04-16
The last revision was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.24
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA demethylase ALKBH5
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH5, ABH5, OFOXD1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: RNA demethylase ALKBH5
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH5, ABH5, OFOXD1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MN, AKG, UNX, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4octA (A:)
gqqlqkeeearkvksgirqmrlfsqdecakiearidevvsraekglynehtvdraplrnk
yffgegytygaqlqkrgpgqerlyppgdvdeipewvhqlviqklvehrvipegfvnsavi
ndyqpggcivshvdpihiferpivsvsffsdsalcfgckfqfkpirvsepvlslpvrrgs
vtvlsgyaadeithcirpqdikerraviilrktrldaprlet

    Sequence, based on observed residues (ATOM records):
    >4octA (A:)
qkeeearkvksgirqmrlfsqdecakiearidevvsraekglynehtvdraplrnkyffg
egytrgpgqerlyppgdvdeipewvhqlviqklvehrvipegfvnsavindyqpggcivs
hvdpihiferpivsvsffsdsalcfgckfqfkpirvsepvlslpvrrgsvtvlsgyaade
ithcirpqdikerraviilrktrldaprle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4octB (B:)
gqqlqkeeearkvksgirqmrlfsqdecakiearidevvsraekglynehtvdraplrnk
yffgegytygaqlqkrgpgqerlyppgdvdeipewvhqlviqklvehrvipegfvnsavi
ndyqpggcivshvdpihiferpivsvsffsdsalcfgckfqfkpirvsepvlslpvrrgs
vtvlsgyaadeithcirpqdikerraviilrktrldaprlet

    Sequence, based on observed residues (ATOM records):
    >4octB (B:)
lqkeeearkvksgirqmrlfsqdecakiearidevvsraekglynehtvdraplrnkyff
gegytgpgqerlyppgdvdeipewvhqlviqklvehrvipegfvnsavindyqpggcivs
hvdpihiferpivsvsffsdsalcfgckfqfkpirvsepvlslpvrrgsvtvlsgyaade
ithcirpqdikerraviilrktrldaprle