PDB entry 4ocm

View 4ocm on RCSB PDB site
Description: Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib
Class: hydrolase, protein binding
Keywords: 26S proteasome, isopeptidase activity, regulatory particle, lid, ubiquitin, HYDROLASE, PROTEIN BINDING
Deposited on 2014-01-09, released 2014-01-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 26s proteasome regulatory subunit rpn8
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: O5360, RPN8, YOR261C
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08723 (Start-177)
      • see remark 999 (178)
    Domains in SCOPe 2.07: d4ocma_
  • Chain 'B':
    Compound: 26s proteasome regulatory subunit rpn11
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: MPR1, RPN11, YFR004W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ocmb_
  • Chain 'C':
    Compound: Nb1
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4OCM
    Domains in SCOPe 2.07: d4ocmc_
  • Chain 'D':
    Compound: 26s proteasome regulatory subunit rpn8
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: O5360, RPN8, YOR261C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ocmd_
  • Chain 'E':
    Compound: 26s proteasome regulatory subunit rpn11
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: MPR1, RPN11, YFR004W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ocme_
  • Chain 'F':
    Compound: Nb1
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4OCM
    Domains in SCOPe 2.07: d4ocmf_
  • Heterogens: ZN, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4ocmA (A:)
    ghmslqhekvtiaplvllsaldhyertqtkenkrcvgvilgdansstirvtnsfalpfee
    deknsdvwfldhnyienmnemckkinakekligwyhsgpklrasdlkinelfkkytqnnp
    lllivdvkqqgvglptdayvaieqvkddgtstektflhlpctieaeeaeeigvehllrgs
    ggsggsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmA (A:)
    hekvtiaplvllsaldhyertqtkenkrcvgvilgdansstirvtnsfalpfeedeknsd
    vwfldhnyienmnemckkinakekligwyhsgpklrasdlkinelfkkytqnnplllivd
    vkqqgvglptdayvaieqktflhlpctieaeeaeeigvehllrg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4ocmB (B:)
    merlqrlmmnskvgsadtgrddtketvyissiallkmlkhgragvpmevmglmlgefvdd
    ytvnvvdvfampqsgtgvsveavddvfqakmmdmlkqtgrdqmvvgwyhshpgfgcwlss
    vdvntqksfeqlnsravavvvdpiqsvkgkvvidafrlidtgalinnleprqttsntgll
    nkaniqalihglnrhyyslnidyhktaketkmlmnlhkeq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmB (B:)
    tketvyissiallkmlkhgragvpmevmglmlgefvddytvnvvdvfampqsgvsveavd
    dvfqakmmdmlkqtgrdqmvvgwyhshpgfgcwlssvdvntqksfeqlnsravavvvdpi
    qsvkgkvvidafrlidtgllnkaniqalihglnrhyyslnidyhktaketkmlmnlh
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4ocmC (C:)
    mqvqlqesggglvpaggslrlscvdsgrtfsstvmawfrqapgkerefvatirwsggnty
    yadsvkgrftisrdnarntvylqmnslkpedtavyycaggtyygtlsykydfwgrgtqvt
    vsshhhhhhepea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmC (C:)
    vqlqesggglvpaggslrlscvdsgrtfsstvmawfrqapgkerefvatirwsggntyya
    dsvkgrftisrdnarntvylqmnslkpedtavyycaggtyygtlsykydfwgrgtqvtvs
    shhhh
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4ocmD (D:)
    ghmslqhekvtiaplvllsaldhyertqtkenkrcvgvilgdansstirvtnsfalpfee
    deknsdvwfldhnyienmnemckkinakekligwyhsgpklrasdlkinelfkkytqnnp
    lllivdvkqqgvglptdayvaieqvkddgtstektflhlpctieaeeaeeigvehllrgs
    ggsggsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmD (D:)
    hekvtiaplvllsaldhyertqtkenkrcvgvilgdansstirvtnsfalpfeedeknsd
    vwfldhnyienmnemckkinakekligwyhsgpklrasdlkinelfkkytqnnplllivd
    vkqqgvglptdayvaieqvtektflhlpctieaeeaeeigvehllr
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4ocmE (E:)
    merlqrlmmnskvgsadtgrddtketvyissiallkmlkhgragvpmevmglmlgefvdd
    ytvnvvdvfampqsgtgvsveavddvfqakmmdmlkqtgrdqmvvgwyhshpgfgcwlss
    vdvntqksfeqlnsravavvvdpiqsvkgkvvidafrlidtgalinnleprqttsntgll
    nkaniqalihglnrhyyslnidyhktaketkmlmnlhkeq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmE (E:)
    tketvyissiallkmlkhgragvpmevmglmlgefvddytvnvvdvfampqsgtgvsvea
    vddvfqakmmdmlkqtgrdqmvvgwyhshpgfgcwlssvdvntqksfeqlnsravavvvd
    piqsvkgkvvidafrlidtgalinnlnkaniqalihglnrhyyslnidyhktaketkmlm
    nlhk
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4ocmF (F:)
    mqvqlqesggglvpaggslrlscvdsgrtfsstvmawfrqapgkerefvatirwsggnty
    yadsvkgrftisrdnarntvylqmnslkpedtavyycaggtyygtlsykydfwgrgtqvt
    vsshhhhhhepea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ocmF (F:)
    vqlqesggglvpaggslrlscvdsgrtfsstvmawfrqapgkerefvatirwsggntyya
    dsvkgrftisrdnarntvylqmnslkpedtavyycaggtyygtlsykydfwgrgtqvtvs
    shhhh