PDB entry 4obo

View 4obo on RCSB PDB site
Description: MAP4K4 in complex with inhibitor (compound 22), 6-(3-CHLOROPHENYL)QUINAZOLIN-4-AMINE
Class: transferase/transferase inhibitor
Keywords: kinase, transferase-transferase inhibitor complex
Deposited on 2014-01-07, released 2014-04-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase kinase kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: HGK, KIAA0687, MAP4K4, NIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4oboa_
  • Chain 'B':
    Compound: Mitogen-activated protein kinase kinase kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: HGK, KIAA0687, MAP4K4, NIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4obob_
  • Heterogens: MES, NA, 2QV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4oboA (A:)
gsandspakslvdidlsslrdpagifelvevvgngtygqvykgrhvktgqlaaikvmdvt
edeeeeikleinmlkkyshhrniatyygafikksppghddqlwlvmefcgagsitdlvkn
tkgntlkedwiayisreilrglahlhihhvihrdikgqnvlltenaevklvdfgvsaqld
rtvgrrntfigtpywmapeviacdenpdatydyrsdlwscgitaiemaegapplcdmhpm
ralfliprnppprlkskkwskkffsfiegclvknymqrpsteqllkhpfirdqpnerqvr
iqlkdhidrtrkkrgekdeteyeysgseegns

    Sequence, based on observed residues (ATOM records): (download) 
    >4oboA (A:)
sslrdpagifelvevvgngtygqvykgrhvktgqlaaikvmdvteikleinmlkkyshhr
niatyygafikksddqlwlvmefcgagsitdlvkntkgntlkedwiayisreilrglahl
hihhvihrdikgqnvlltenaevklvdfgrntfigtpywmapeviacdenpdatydyrsd
lwscgitaiemaegapplcdmhpmralfliprnppprlkskkwskkffsfiegclvknym
qrpsteqllkhpfirdqpnerqvriqlkdhidrtr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4oboB (B:)
gsandspakslvdidlsslrdpagifelvevvgngtygqvykgrhvktgqlaaikvmdvt
edeeeeikleinmlkkyshhrniatyygafikksppghddqlwlvmefcgagsitdlvkn
tkgntlkedwiayisreilrglahlhihhvihrdikgqnvlltenaevklvdfgvsaqld
rtvgrrntfigtpywmapeviacdenpdatydyrsdlwscgitaiemaegapplcdmhpm
ralfliprnppprlkskkwskkffsfiegclvknymqrpsteqllkhpfirdqpnerqvr
iqlkdhidrtrkkrgekdeteyeysgseegns

    Sequence, based on observed residues (ATOM records): (download) 
    >4oboB (B:)
didlsslrdpagifelvevvgngqvykgrhvktgqlaaikvmdvtedeeeeikleinmlk
kyshhrniatyygafikksppghddqlwlvmefcgagsitdlvkntkgntlkedwiayis
reilrglahlhihhvihrdikgqnvlltenaevklvdfgvsaqldrtvgrrntfigtpyw
mapeviacdenpdatydyrsdlwscgitaiemaegapplcdmhpmralfliprnppprlk
skkwskkffsfiegclvknymqrpsteqllkhpfirdqpnerqvriqlkdhidrtrk