PDB entry 4o8z

View 4o8z on RCSB PDB site
Description: Crystal structure of human SIRT3 in complex with compound (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone
Class: hydrolase
Keywords: mitochondria NAD+-dependent deacetylase, HYDROLASE
Deposited on 2013-12-31, released 2015-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-04-22, with a file datestamp of 2015-04-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4o8za_
  • Heterogens: ZN, BBI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4o8zA (A:)
hhhhhhdydipttenlyfqgssdkgklslqdvaeliraracqrvvvmvgagistpsgipd
frspgsglysnlqqydlpypeaifelpfffhnpkpfftlakelypgnykpnvthyflrll
hdkglllrlytqnidglervsgipasklveahgtfasatctvcqrpfpgediradvmadr
vprcpvctgvvkpdivffgeplpqrfllhvvdfpmadlllilgtslevepfaslteavrs
svprllinrdlvgplawhprsrdvaqlgdvvhgveslvellgwteemrdlvqretgkldg
pdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o8zA (A:)
klslqdvaeliraracqrvvvmvgagistpsgipdfspgsglysnlqqydlpypeaifel
pfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipas
klveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqrf
llhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdvaq
lgdvvhgveslvellgwteemrdlvqretgkl