PDB entry 4o6w

View 4o6w on RCSB PDB site
Description: Peptide-Based Inhibitors of Plk1 Polo-box Domain
Class: transferase/transferase inhibitor
Keywords: Polo box domain, phospho-peptide binding, phosphopeptide, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-12-23, released 2014-12-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-03, with a file datestamp of 2014-11-28.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: 0.185
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4o6wa1, d4o6wa2
  • Chain 'C':
    Compound: peptide-based inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 4O6W
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4o6wA (A:)
gahmdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyq
lcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnym
sehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcpl
maavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas

    Sequence, based on observed residues (ATOM records): (download) 
    >4o6wA (A:)
hlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdnsv
gvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehllk
aganitprerlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekr
dfrtyrlslleeygcckelasrlryartmvdkllssr

  • Chain 'C':
    No sequence available.