PDB entry 4o69

View 4o69 on RCSB PDB site
Description: Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion
Deposited on 2013-12-20, released 2014-02-05
The last revision was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.191
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: MB21D1, C6orf150
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N884 (1-End)
      • expression tag (0)
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4o69A (A:)
    mgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyyehvk
    isapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskmlsk
    frkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqeglr
    iqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktccen
    keekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrkd
    lglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnefpvf
    def
    

    Sequence, based on observed residues (ATOM records):
    >4o69A (A:)
    mgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyyehvk
    isapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskmlsk
    frkiikeeinditdvimkrkrgpavtllisekisvditlalesksswpastqeglriqnw
    lsakvrkqlrlkpfylvpkhakqeetwrlsfshiekeilnnhgksktccenkeekccrkd
    clklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrkdlglcfdncv
    tyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnefpvfde