PDB entry 4o5l

View 4o5l on RCSB PDB site
Description: Crystal structure of broadly neutralizing antibody F045-092
Class: immune system
Keywords: Fab, Fragment antigen binding, Immunoglobulin fold, immune system
Deposited on 2013-12-19, released 2014-04-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-21, with a file datestamp of 2017-06-16.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab F045-092 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4O5L (0-102)
    • Uniprot A8K008 (118-233)
      • expression tag (234-239)
    Domains in SCOPe 2.08: d4o5lh1, d4o5lh2
  • Chain 'L':
    Compound: Fab F045-092 light chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IGLC3
    Database cross-references and differences (RAF-indexed):
    • PDB 4O5L (0-110)
    • Uniprot P0DOY3 (111-End)
    Domains in SCOPe 2.08: d4o5ll1, d4o5ll2
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4o5lH (H:)
evqlvesgaevkkpgssvkvscrasgtfykyainwvrqapgqglewmggiipffgttnya
qkfqgrltitadgstntaymqldslrsedtavyycagpsiteshycldcaakdyyygldv
wgqgttvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsg
vhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4o5lH (H:)
evqlvesgaevkkpgssvkvscrasgtfykyainwvrqapgqglewmggiipffgttnya
qkfqgrltitadgstntaymqldslrsedtavyycagpsiteshycldcaakdyyygldv
wgqgttvtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4o5lL (L:)
qsvltqppsasgtpgqsvtiscsgsrsniggntvnwyqhlpgmapklliyssnqrssgvp
drfsgsksgtsaslaisglqseddadyycaswddslngvvfgggtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshksyscqvthegstvektvaptecsarlgggdykddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o5lL (L:)
qsvltqppsasgtpgqsvtiscsgsrsniggntvnwyqhlpgmapklliyssnqrssgvp
drfsgsksgtsaslaisglqseddadyycaswddslngvvfgggtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshksyscqvthegstvektvaptec