PDB entry 4o43

View 4o43 on RCSB PDB site
Description: dna double-strand break repair pathway choice is directed by distinct mre11 nuclease activities
Deposited on 2013-12-18, released 2014-01-08
The last revision was dated 2020-02-19, with a file datestamp of 2020-02-14.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Exonuclease, putative
    Species: Thermotoga maritima [TaxId:243274]
    Gene: TM_1635
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X1X0 (Start-335)
      • expression tag (5-12)
  • Chain 'B':
    Compound: Exonuclease, putative
    Species: Thermotoga maritima [TaxId:243274]
    Gene: TM_1635
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MN, 2PW, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4o43A (A:)
mgsdkihhhhhhvinlkelkilhtsdwhlgvtswtssrpvdrreelkkaldkvveeaekr
evdlilltgdllhsrnnpsvvalhdlldylkrmmrtapvvvlpgnhdwkglklfgnfvts
issditfvmsfepvdveakrgqkvrilpfpypdesealrknegdfrfflesrlnklyeea
lkkedfaifmghftveglagyagieqgreiiinralipsvvdyaalghihsfreiqkqpl
tiypgsliridfgeeadekgavfvelkrgeppryeridasplplktlyykkidtsalksi
rdfcrnfpgyvrvvyeedsgilpdlmgeidnlvkie

    Sequence, based on observed residues (ATOM records):
    >4o43A (A:)
ihhhhhhvinlkelkilhtsdwhlgvtswtssrpvdrreelkkaldkvveeaekrevdli
lltgdllhsrnnpsvvalhdlldylkrmmrtapvvvlpgnhdwkglklfgnfvtsissdi
tfvmsfepvdveakrgqkvrilpfpypdesealrknegdfrfflesrlnklyeealkked
faifmghftveglagyagieqgreiiinralipsvvdyaalghihsfreiqkqpltiypg
sliridfgeeadekgavfvelkrgeppryeridasplplktlyykkidtsalksirdfcr
nfpgyvrvvyeedsgilpdlmgeidnlvkie

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4o43B (B:)
mgsdkihhhhhhvinlkelkilhtsdwhlgvtswtssrpvdrreelkkaldkvveeaekr
evdlilltgdllhsrnnpsvvalhdlldylkrmmrtapvvvlpgnhdwkglklfgnfvts
issditfvmsfepvdveakrgqkvrilpfpypdesealrknegdfrfflesrlnklyeea
lkkedfaifmghftveglagyagieqgreiiinralipsvvdyaalghihsfreiqkqpl
tiypgsliridfgeeadekgavfvelkrgeppryeridasplplktlyykkidtsalksi
rdfcrnfpgyvrvvyeedsgilpdlmgeidnlvkie

    Sequence, based on observed residues (ATOM records):
    >4o43B (B:)
lkelkilhtsdwhlgvtswtssrpvdrreelkkaldkvveeaekrevdlilltgdllhsr
nnpsvvalhdlldylkrmmrtapvvvlpgnhdwkglklfgnfvtsissditfvmsfepvd
veakrgqkvrilpfpypdesealrknegdfrfflesrlnklyeealkkedfaifmghftv
eglagyagieqgreiiinralipsvvdyaalghihsfreiqkqpltiypgsliridfgee
adekgavfvelkrgeppryeridasplplktlyykkidtsalksirdfcrnfpgyvrvvy
eedsgilpdlmgeidnlvkie