PDB entry 4o3x

View 4o3x on RCSB PDB site
Description: Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Phe-171-Ala from Actinobacillus pleuropneumoniae H49
Class: metal transport
Keywords: Structure-based vaccine design, transferrin receptor, iron acquisition, host pathogen interaction, surface lipoprotein, METAL TRANSPORT
Deposited on 2013-12-18, released 2015-01-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-03-04, with a file datestamp of 2015-02-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Transferrin binding protein B
    Species: Actinobacillus pleuropneumoniae [TaxId:715]
    Gene: tbpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot G0T4F6
      • engineered mutation (136)
    Domains in SCOPe 2.08: d4o3xb1, d4o3xb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4o3xB (B:)
gseqlgelmepalgyvvkvpvssfenkkvdisdievitngnlddvpykansskynypdik
tkdsslqyvrsgyvidgehsgsnekgyvyykgnspakelpvnqlltytgswdftsnanln
neegrpnylnddyytkaigkrvglvsgdakpakhkytsqfevdfatkkmtgklsdkekti
ytvnadirgnrftgaatasdknkgkgesynffsadsqsleggfygpkaeemagkfvandk
slfavfsakhngsnv

    Sequence, based on observed residues (ATOM records): (download) 
    >4o3xB (B:)
palgyvvkvpvssfenkkvdisdievitngnlddvpykansskynypdiktkdsslqyvr
sgyvidgehsgsnekgyvyykgnspakelpvnqlltytgswdftsnanlnneegrpnyln
ddyytkaigkrvglvsgdakpakhkytsqfevdfatkkmtgklsdkektiytvnadirgn
rftgaatasdknkgkgesynffsadsqsleggfygpkaeemagkfvandkslfavfsakh
n