PDB entry 4o3t

View 4o3t on RCSB PDB site
Description: zymogen hgf-beta/met with zymogen activator peptide zap.14
Deposited on 2013-12-18, released 2014-06-04
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.99 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hepatocyte growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: HGF, HPTA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14210
      • engineered mutation (109)
  • Chain 'B':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: zap.14
    Species: synthetic, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 4O3T (0-End)
  • Heterogens: 1PE

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4o3tA (A:)
gvngiptrtnigwmvslryrnkhicggslikeswvltarqcfpsrdlkdyeawlgihdvh
grgdekckqvlnvsqlvygpegsdlvlmklarpavlddfvstidlpnygstipektscsv
ygwgytglinydgllrvahlyimgnekcsqhhrgkvtlneseicagaekigsgpcegdyg
gplvceqhkmrmvlgvivpgrgcaipnrpgifvrvayyakwihkiiltykvpqshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4o3tA (A:)
nigwmvslryrnkhicggslikeswvltarqcfpsrdlkdyeawlgihdvhgrgdekckq
vlnvsqlvygpegsdlvlmklarpavlddfvstidlpnygstipektscsvygwgytgli
nydgllrvahlyimgnekcsqhhrgkvtlneseicagaekigsgpcegdyggplvceqhk
mrmvlgvivpgrgcaipnrpgifvrvayyakwihkiilt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4o3tB (B:)
eckealaksemnvnmkyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaey
ktgpvlehpdcfpcqdcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrh
vfphnhtadiqsevhcifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinss
yfpdhplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltv
qretldaqtfhtriirfcsinsglhsymempleciltekrkkrstkkevfnilqaayvsk
pgaqlarqigaslnddilfgvfaqskpdsaepmdrsamcafpikyvndffnkivnknnvr
clqhfygpnhehcfnrtllrnssgcearrdeyrtefttalqrvdlfmgqfsevlltsist
fikgdltianlgtsegrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngytlv
itgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqiclpa
iykhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >4o3tB (B:)
kyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlehpdcfpcq
dcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrhvfphnhtadiqsevh
cifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinssyfpdhplhsisvrrl
ketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltvqretldaqtfhtrii
rfcsinsglhsymempleciltkevfnilqaayvskpgaqlarqigaslnddilfgvfaq
skpdsaepmdrsamcafpikyvndffnkinvrclqhfygpnhehcfnrdeyrtefttalq
rvdlfmgqfsevlltsistfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshp
vspevivehtlnqngytlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkc
vrseeclsgtwtqqiclpa

  • Chain 'P':
    Sequence, based on SEQRES records:
    >4o3tP (P:)
ivggypwwmdv

    Sequence, based on observed residues (ATOM records):
    >4o3tP (P:)
ivggypwwm