PDB entry 4o3p

View 4o3p on RCSB PDB site
Description: Crystal structure of human polymerase eta inserting dctp opposite an 8-oxog containing dna template
Deposited on 2013-12-18, released 2014-04-30
The last revision was dated 2014-07-02, with a file datestamp of 2014-06-27.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.165
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA Polymerase ETA
    Species: Homo sapiens [TaxId:9606]
    Gene: POLH, RAD30, RAD30A, XPV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y253 (3-434)
      • expression tag (0-2)
  • Chain 'P':
    Compound: DNA (5'-d(*ap*gp*cp*gp*tp*cp*ap*t)-3')
    Species: synthetic, synthetic
  • Chain 'T':
    Compound: DNA (5'-d(*cp*ap*tp*(8og)p*ap*tp*gp*ap*cp*gp*cp*t)-3')
    Species: synthetic, synthetic
  • Heterogens: 0KX, MG, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4o3pA (A:)
gphmatgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearaf
gvtrsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasidea
yvdltsavqerlqklqgqpisadllpstyieglpqgpttaeetvqkegmrkqglfqwlds
lqidnltspdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtl
vshgsvpqlfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngsw
lyamcrgiehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrn
dndrvatqlvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewsp
pltmlflcatkfsas

    Sequence, based on observed residues (ATOM records):
    >4o3pA (A:)
gphmatgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearaf
gvtrsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasidea
yvdltsavqerlqklqgqpisadllpstyieglpqgpttvqkegmrkqglfqwldslqid
nltspdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtlvshg
svpqlfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngswlyam
crgiehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrndndr
vatqlvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewsppltm
lflcatkfsas

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.