PDB entry 4o33

View 4o33 on RCSB PDB site
Description: Crystal Structure of human PGK1 3PG and terazosin(TZN) ternary complex
Class: transferase/transferase activator
Keywords: ENZYME-DRUG COMPLEX, TRANSFERASE-TRANSFERASE ACTIVITOR complex, TRANSFERASE-TRANSFERASE ACTIVATOR complex
Deposited on 2013-12-18, released 2014-10-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-31, with a file datestamp of 2014-12-26.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.196
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglycerate kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGK1, PGKA, MIG10, OK/SW-cl.110
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00558 (0-416)
      • conflict (369)
    Domains in SCOPe 2.08: d4o33a_
  • Heterogens: TZN, 3PG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4o33A (A:)
    mslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvl
    mshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsville
    nlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvn
    lpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggm
    aftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgq
    atvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevv
    katsrgcittigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni