PDB entry 4o2l

View 4o2l on RCSB PDB site
Description: Structure of Mus musculus Rheb G63A mutant bound to GTP
Class: hydrolase
Keywords: Small GTPase, Hydrolase, GDP and GTP
Deposited on 2013-12-17, released 2014-03-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.195
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding protein Rheb
    Species: Mus musculus [TaxId:10090]
    Gene: Rheb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q921J2 (Start-170)
      • engineered mutation (64)
    Domains in SCOPe 2.06: d4o2la_
  • Chain 'B':
    Compound: GTP-binding protein Rheb
    Species: Mus musculus [TaxId:10090]
    Gene: Rheb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q921J2 (Start-170)
      • engineered mutation (64)
    Domains in SCOPe 2.06: d4o2lb_
  • Heterogens: GTP, MG, TRS, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4o2lA (A:)
gsmpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlql
vdtaaqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvg
nkkdlhmervisyeegkalaeswnaaflessakenqtavdvfkriileaek

    Sequence, based on observed residues (ATOM records): (download) 
    >4o2lA (A:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
aqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfkriileaek

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4o2lB (B:)
gsmpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlql
vdtaaqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvg
nkkdlhmervisyeegkalaeswnaaflessakenqtavdvfkriileaek

    Sequence, based on observed residues (ATOM records): (download) 
    >4o2lB (B:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
aqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfkriileaek