PDB entry 4o1e

View 4o1e on RCSB PDB site
Description: Structure of a methyltransferase component in complex with MTHF involved in O-demethylation
Class: transferase
Keywords: TIM barrel, methyltransferase, THF/MTHF, TRANSFERASE
Deposited on 2013-12-15, released 2015-01-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-09-16, with a file datestamp of 2015-09-11.
Experiment type: XRAY
Resolution: 1.61 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydropteroate synthase DHPS
    Species: Desulfitobacterium hafniense [TaxId:272564]
    Gene: Dhaf_0722
    Database cross-references and differences (RAF-indexed):
    • Uniprot B8FW00 (22-End)
      • expression tag (17-21)
    Domains in SCOPe 2.08: d4o1ea1, d4o1ea2
  • Chain 'B':
    Compound: Dihydropteroate synthase DHPS
    Species: Desulfitobacterium hafniense [TaxId:272564]
    Gene: Dhaf_0722
    Database cross-references and differences (RAF-indexed):
    • Uniprot B8FW00 (22-End)
      • expression tag (19-21)
    Domains in SCOPe 2.08: d4o1eb1, d4o1eb2
  • Heterogens: C2F, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4o1eA (A:)
mgsshhhhhhssglvprgshmliiigekingtipsvkkaieakdeklirdlalrqseaga
dyidvcastspelevetlqwlmdivqeatdtplcidspnpraiqqvllyakrpglinsvs
legdkcevifpliqgtswqvialtcdnsgipqdvqsrveiaqalvekaqsydiaqerihi
dplvialsadngallkfaeatrqikanypminvtsglsnisfgmplrkvvnqnfltlamf
agmdsaildplnrdllaallateallgrdkhcrnfanayrknkigplkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >4o1eA (A:)
gshmliiigekingtipsvkkaieakdeklirdlalrqseagadyidvcastspelevet
lqwlmdivqeatdtplcidspnpraiqqvllyakrpglinsvslegdkcevifpliqgts
wqvialtcdnsgipqdvqsrveiaqalvekaqsydiaqerihidplvialsadngallkf
aeatrqikanypminvtsglsnisfgmplrkvvnqnfltlamfagmdsaildplnrdlla
allateallgrdkhcrnfanayrknkigplk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4o1eB (B:)
mgsshhhhhhssglvprgshmliiigekingtipsvkkaieakdeklirdlalrqseaga
dyidvcastspelevetlqwlmdivqeatdtplcidspnpraiqqvllyakrpglinsvs
legdkcevifpliqgtswqvialtcdnsgipqdvqsrveiaqalvekaqsydiaqerihi
dplvialsadngallkfaeatrqikanypminvtsglsnisfgmplrkvvnqnfltlamf
agmdsaildplnrdllaallateallgrdkhcrnfanayrknkigplkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >4o1eB (B:)
hmliiigekingtipsvkkaieakdeklirdlalrqeagadyidvcastspelevetlqw
lmdivqeatdtplcidspnpraiqqvllyakrpglinsvslegdkcevifpliqgtswqv
ialtcdnsgipqdvqsrveiaqalvekaqsydiaqerihidplvialsadngallkfaea
trqikanypminvtsglsnisfgmplrkvvnqnfltlamfagmdsaildplnrdllaall
ateallgrdkhcrnfanayrknkigpl