PDB entry 4nwc

View 4nwc on RCSB PDB site
Description: Crystal structure of the GluK3 ligand-binding domain (S1S2) in complex with the agonist (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic acid at 2.01 A resolution.
Class: MEMBRANE PROTEIN, RECEPTOR/Agonist
Keywords: Kainate receptor ligand-binding domain, Agonist, Ionotropic glutamate receptor, MEMBRANE PROTEIN, RECEPTOR-Agonist complex
Deposited on 2013-12-06, released 2014-08-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, kainate 3
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur7, Grik3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42264 (3-117)
      • linker (118-119)
    • Uniprot P42264 (120-257)
    Domains in SCOPe 2.08: d4nwca_
  • Heterogens: K, PO4, CL, 2QE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4nwcA (A:)
    gpgtnrslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlved
    gkygaqddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgt
    pidsaddlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqr
    tltadyallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqe
    edklhimkekwwrgsgcp
    

    Sequence, based on observed residues (ATOM records): (download)
    >4nwcA (A:)
    tnrslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlvedgky
    gaqddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgtpid
    saddlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqrtlt
    adyallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqeedk
    lhimkekwwrgsgcp