PDB entry 4nuv

View 4nuv on RCSB PDB site
Description: Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Class: membrane protein, cell invasion
Keywords: Duffy Binding Like (DBL) Domain Fold, GPCR, Adhesion, Invasion, Red blood cell binding, Chemokine Binding, Duffy Antigen Receptor for Chemokines, Membrane, membrane protein, protein binding, cell invasion
Deposited on 2013-12-04, released 2014-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Duffy receptor
    Species: Plasmodium vivax [TaxId:126793]
    Gene: PVDR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nuva_
  • Chain 'B':
    Compound: Duffy receptor
    Species: Plasmodium vivax [TaxId:126793]
    Gene: PVDR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nuvb_
  • Chain 'C':
    Compound: Duffy antigen/chemokine receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: DARC, ACKR1, FY, GPD
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Duffy antigen/chemokine receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: DARC, ACKR1, FY, GPD
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nuvA (A:)
asntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfr
klylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvv
ennlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepq
iyrwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkkn
qwdvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcs
veeakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nuvA (A:)
ntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvfhrditfrklylkrkl
iydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsif
gtdekaqqrrkqwwneskaqiwtammysvkkrlfiwicklnvavniepqiyrwirewgrd
yvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqwdvlsnkfis
vknaekqtagivtpydilkqeldefnevafeneinkrdgayielcvcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nuvB (B:)
asntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfr
klylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvv
ennlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepq
iyrwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkkn
qwdvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcs
veeakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nuvB (B:)
mkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvhrditfrklylkrkliyda
avegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsifgtde
kaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiyrwirewgrdy
vselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqwdvlsnkfisv
knaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcs

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.