PDB entry 4nuu

View 4nuu on RCSB PDB site
Description: Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Class: membrane protein, cell invasion
Keywords: Duffy Binding Like (DBL) Domain Fold, GPCR, Adhesion, Invasion, Red blood cell binding, Chemokine Binding, Duffy Antigen Receptor for Chemokines, Membrane, membrane protein, protein binding, cell invasion
Deposited on 2013-12-04, released 2014-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Duffy receptor
    Species: Plasmodium vivax [TaxId:126793]
    Gene: PVDR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22290 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d4nuua1, d4nuua2
  • Chain 'B':
    Compound: Duffy receptor
    Species: Plasmodium vivax [TaxId:126793]
    Gene: PVDR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22290 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d4nuub1, d4nuub2
  • Chain 'C':
    Compound: Duffy antigen/chemokine receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: DARC, ACKR1, FY, GPD
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nuuA (A:)
asntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfr
klylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvv
ennlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepq
iyrwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkkn
qwdvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcs
veeakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nuuA (A:)
sntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvitfrklylkrkliyd
aavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsifgtd
ekaqqrrkqwwneskaqiwtammysvkkrlkicklnvavniepqiyrwirewgrdyvsel
ptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqwdvlsnkfisvknae
qtagivtpydilkqeldefnevafeneinkrdgayielcvcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nuuB (B:)
asntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfr
klylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvv
ennlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepq
iyrwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkkn
qwdvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcs
veeakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nuuB (B:)
asntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlfhrditfrklylkrk
liydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsi
fgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiyrwire
wgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqwdvlsn
kfisvknaekqtagivtpydilkqeldefnevafeneinkrdgayielcvcs

  • Chain 'C':
    No sequence available.