PDB entry 4nus

View 4nus on RCSB PDB site
Description: Rsk2 N-terminal kinase in complex with LJH685
Class: transferase/transferase inhibitor
Keywords: kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-12-04, released 2014-03-05
The last revision prior to the SCOPe 2.03 freeze date was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: 0.191
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosomal protein S6 kinase alpha-3
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KA3, ISPK1, MAPKAPK1B, RSK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4nusa_
  • Heterogens: 2NK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nusA (A:)
gpnpqteevsikeiaithhvkeghekadpsqfellkvlgqgsfgkvflvkkisgsdarql
yamkvlkkatlkvrdrvrtkmerdilvevnhpfivklhyafqtegklylildflrggdlf
trlskevmfteedvkfylaelalaldhlhslgiiyrdlkpenilldeeghikltdfglsk
esidhekkaysfcgtveymapevvnrrghtqsadwwsfgvlmfemltgtlpfqgkdrket
mtmilkaklgmpqflspeaqsllrmlfkrnpanrlgagpdgveeikrhsffstidwnkly
rreihppfkpatgrpedtfyfdp

    Sequence, based on observed residues (ATOM records): (download) 
    >4nusA (A:)
thhvkeghekadpsqfellkvlgqgsfgkvflvkkisgsdarqlyamkvlkkatlkvrdr
vrtkmerdilvevnhpfivklhyafqtegklylildflrggdlftrlskevmfteedvkf
ylaelalaldhlhslgiiyrdlkpenilldeeghikltdfglskesidhekkaysfcgtv
eymapevvnrrghtqsadwwsfgvlmfemltgtlpfqgkdrketmtmilkaklgmpqfls
peaqsllrmlfkrnpanrlgagpdgveeikrhsffstidwnklyrreihppfkpatfyfd
p