PDB entry 4nue
View 4nue on RCSB PDB site
Description: Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor
Class: transcription/transcription inhibitor
Keywords: transcription factor, transcription, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex
Deposited on
2013-12-03, released
2014-04-02
The last revision prior to the SCOPe 2.05 freeze date was dated
2014-04-02, with a file datestamp of
2014-03-28.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.14
AEROSPACI score: 0.7
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4nuea_ - Heterogens: NUE, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4nueA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee
Sequence, based on observed residues (ATOM records): (download)
>4nueA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelpte