PDB entry 4nsl

View 4nsl on RCSB PDB site
Description: X-ray Crystal structure of Adenylosuccinate Lyase from Salmonella typhimurium
Class: lyase
Keywords: Purine biosynthesis, homotetramer, aspartase/fumarase superfamily, lyase, interface binding site
Deposited on 2013-11-28, released 2014-12-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.223
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenylosuccinate lyase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: purB, STM1232
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nsla_
  • Chain 'B':
    Compound: adenylosuccinate lyase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: purB, STM1232
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nslb_
  • Chain 'C':
    Compound: adenylosuccinate lyase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: purB, STM1232
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nslc_
  • Chain 'D':
    Compound: adenylosuccinate lyase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: purB, STM1232
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nsld_
  • Heterogens: N2P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nslA (A:)
mrgshhhhhhgmasmelssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqk
laahaaikevpafaadangyldtlvanfneedaariktierttnhdvkaveyflkekvaa
ipalhdvsefihfactsedinnlshalmlktardevilpywrqvinavkdlatqyrdipl
lsrthgqpatpstlgkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdw
hqfseefvtslgiqwnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkq
ktiageigsstmphkvnpidfensegnlglsnavlhhlanklpvsrwqrdltdstvlrnl
gvgigyaliayqstlkgvsklevnrdhlldeldhnwevlaepiqtvmrrygiekpyeklk
eltrgkrvdaegmkqfidslalpeaektrlkamtpanyigravtlvdelk

    Sequence, based on observed residues (ATOM records): (download) 
    >4nslA (A:)
melssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqklaahaaikevpafa
adangyldtlvanfneedaariktierttnhdvkaveyflkekvaaipalhdvsefihfa
ctsedinnlshalmlktardevilpywrqvinavkdlatqyrdipllsrthgqpatpstl
gkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdwhqfseefvtslgiq
wnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkqktmphkvnpidfen
segnlglsnavlhhlanklpvsrwqrdltdstvlrnlgvgigyaliayqstlkgvsklev
nrdhlldeldhnwevlaepiqtvmrrygiekpyeklkeltrkrvdaegmkqfidslalpe
aektrlkamtpanyigravtlvdelk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nslB (B:)
mrgshhhhhhgmasmelssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqk
laahaaikevpafaadangyldtlvanfneedaariktierttnhdvkaveyflkekvaa
ipalhdvsefihfactsedinnlshalmlktardevilpywrqvinavkdlatqyrdipl
lsrthgqpatpstlgkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdw
hqfseefvtslgiqwnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkq
ktiageigsstmphkvnpidfensegnlglsnavlhhlanklpvsrwqrdltdstvlrnl
gvgigyaliayqstlkgvsklevnrdhlldeldhnwevlaepiqtvmrrygiekpyeklk
eltrgkrvdaegmkqfidslalpeaektrlkamtpanyigravtlvdelk

    Sequence, based on observed residues (ATOM records): (download) 
    >4nslB (B:)
melssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqklaahaaikevpafa
adangyldtlvanfneedaariktierttnhdvkaveyflkekvaaipalhdvsefihfa
ctsedinnlshalmlktardevilpywrqvinavkdlatqyrdipllsrthgqpatpstl
gkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdwhqfseefvtslgiq
wnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkqktiaghkvnpidfe
nsegnlglsnavlhhlanklpvsrwqrdltdstvlrnlgvgigyaliayqstlkgvskle
vnrdhlldeldhnwevlaepiqtvmrrygiekpyeklkeltrkrvdaegmkqfidslalp
eaektrlkamtpanyigravtlvdelk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4nslC (C:)
mrgshhhhhhgmasmelssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqk
laahaaikevpafaadangyldtlvanfneedaariktierttnhdvkaveyflkekvaa
ipalhdvsefihfactsedinnlshalmlktardevilpywrqvinavkdlatqyrdipl
lsrthgqpatpstlgkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdw
hqfseefvtslgiqwnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkq
ktiageigsstmphkvnpidfensegnlglsnavlhhlanklpvsrwqrdltdstvlrnl
gvgigyaliayqstlkgvsklevnrdhlldeldhnwevlaepiqtvmrrygiekpyeklk
eltrgkrvdaegmkqfidslalpeaektrlkamtpanyigravtlvdelk

    Sequence, based on observed residues (ATOM records): (download) 
    >4nslC (C:)
melssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqklaahaaikevpafa
adangyldtlvanfneedaariktierttnhdvkaveyflkekvaaipalhdvsefihfa
ctsedinnlshalmlktardevilpywrqvinavkdlatqyrdipllsrthgqpatpstl
gkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdwhqfseefvtslgiq
wnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkqktphkvnpidfens
egnlglsnavlhhlanklpvsrwqrdltdstvlrnlgvgigyaliayqstlkgvsklevn
rdhlldeldhnwevlaepiqtvmrrygiekpyeklkeltrgkrvdaegmkqfidslalpe
aektrlkamtpanyigravtlvdelk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4nslD (D:)
mrgshhhhhhgmasmelssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqk
laahaaikevpafaadangyldtlvanfneedaariktierttnhdvkaveyflkekvaa
ipalhdvsefihfactsedinnlshalmlktardevilpywrqvinavkdlatqyrdipl
lsrthgqpatpstlgkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdw
hqfseefvtslgiqwnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkq
ktiageigsstmphkvnpidfensegnlglsnavlhhlanklpvsrwqrdltdstvlrnl
gvgigyaliayqstlkgvsklevnrdhlldeldhnwevlaepiqtvmrrygiekpyeklk
eltrgkrvdaegmkqfidslalpeaektrlkamtpanyigravtlvdelk

    Sequence, based on observed residues (ATOM records): (download) 
    >4nslD (D:)
melssltavspvdgrygdkvsalrgifseygllkfrvqvevrwlqklaahaaikevpafa
adangyldtlvanfneedaariktierttnhdvkaveyflkekvaaipalhdvsefihfa
ctsedinnlshalmlktardevilpywrqvinavkdlatqyrdipllsrthgqpatpstl
gkemanvayrmerqfrqlnqveilgkingavgnynahiaaypevdwhqfseefvtslgiq
wnpyttqiephdyiaelfdciarfntilidfdrdvwgyialnhfkqkmphkvnpidfens
egnlglsnavlhhlanklpvsrwqrdltdstvlrnlgvgigyaliayqstlkgvsklevn
rdhlldeldhnwevlaepiqtvmrrygiekpyeklkeltrvdaegmkqfidslalpeaek
trlkamtpanyigravtlvdelk