PDB entry 4nr3
View 4nr3 on RCSB PDB site
Description: Crystal Structure of a human Mms2/Ubc13 L121G mutant
Class: ligase
Keywords: ubc13, mms2, E2, ubiquitin conjugating enzyme, ligase
Deposited on
2013-11-26, released
2014-12-10
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-12-10, with a file datestamp of
2014-12-05.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.19
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin-conjugating enzyme E2 variant 2
Species: Homo sapiens [TaxId:9606]
Gene: MMS2, UBE2V2, UEV2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4nr3a_ - Chain 'B':
Compound: Ubiquitin-conjugating enzyme E2 N
Species: Homo sapiens [TaxId:9606]
Gene: BLU, UBE2N
Database cross-references and differences (RAF-indexed):
- Uniprot P61088 (8-156)
- engineered mutation (127)
Domains in SCOPe 2.04: d4nr3b_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4nr3A (A:)
gplgspefgvkvprnfrlleeleegqkgvgdgtvswgleddedmtltrwtgmiigpprtn
yenriyslkvecgpkypeappsvrfvtkinmnginnssgmvdarsipvlakwqnsysikv
vlqelrrlmmskenmklpqppegqtynn
Sequence, based on observed residues (ATOM records): (download)
>4nr3A (A:)
gvkvprnfrlleeleegqkgvgdgtvswgleddedmtltrwtgmiigpprtnyenriysl
kvecgpkypeappsvrfvtkinmnginnssgmvdarsipvlakwqnsysikvvlqelrrl
mmskenmklpqppegqtynn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4nr3B (B:)
gplgspefaglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfk
lelflpeeypmaapkvrfmtkiyhpnvdklgricldilkdkwspalqirtvllsiqalls
apnpddpgandvaeqwktneaqaietarawtrlyamn
Sequence, based on observed residues (ATOM records): (download)
>4nr3B (B:)
aglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelflpee
ypmaapkvrfmtkiyhpnvdklgricldilkdkwspalqirtvllsiqallsapnpddpg
andvaeqwktneaqaietarawtrlyamn