PDB entry 4nqn

View 4nqn on RCSB PDB site
Description: Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand
Class: transcription/inhibitor
Keywords: STRUCTURAL GENOMICS CONSORTIUM, SGC, BROMODOMAIN, INHIBITION, Transcription, Small molecule inhibitor, TRANSCRIPTION-INHIBITOR complex
Deposited on 2013-11-25, released 2013-12-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-12-18, with a file datestamp of 2013-12-13.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: 0.19
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4nqna_
  • Heterogens: Y1Z, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4nqnA (A:)
    smlklsaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmk
    dkivaneyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkr
    sms
    

    Sequence, based on observed residues (ATOM records): (download)
    >4nqnA (A:)
    estpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyk
    svtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkrsm