PDB entry 4npf
View 4npf on RCSB PDB site
Description: High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker
Class: protein binding
Keywords: SpA, three-helix bundle, conformational heterogeneity, rapidly unfolding and folding, RUF, Antibody binding, Antibody, TNFR1, von Willebrand factor, PROTEIN BINDING
Deposited on
2013-11-21, released
2014-10-08
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-22, with a file datestamp of
2017-11-17.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: Immunoglobulin G-binding protein A
Species: STAPHYLOCOCCUS AUREUS [TaxId:1280]
Gene: protein A, spa
Database cross-references and differences (RAF-indexed):
- Uniprot P38507 (Start-115)
- see remark 999 (3)
- engineered mutation (12)
- see remark 999 (17-18)
- see remark 999 (52-53)
- see remark 999 (70)
- see remark 999 (12)
- engineered mutation (70)
Domains in SCOPe 2.08: d4npfx1, d4npfx2 - Chain 'Y':
Compound: Immunoglobulin G-binding protein A
Species: STAPHYLOCOCCUS AUREUS [TaxId:1280]
Gene: protein A, spa
Database cross-references and differences (RAF-indexed):
- Uniprot P38507 (0-115)
- see remark 999 (3)
- engineered mutation (12)
- see remark 999 (17-18)
- see remark 999 (52-53)
- see remark 999 (70)
- see remark 999 (12)
- engineered mutation (70)
Domains in SCOPe 2.08: d4npfy1, d4npfy2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'X':
Sequence, based on SEQRES records: (download)
>4npfX (X:)
adnkfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapkad
nkfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapk
Sequence, based on observed residues (ATOM records): (download)
>4npfX (X:)
dnkfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapkadn
kfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapk
- Chain 'Y':
Sequence; same for both SEQRES and ATOM records: (download)
>4npfY (Y:)
adnkfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapkad
nkfnkeqqnawyeilhlpnlneeqrngfiqslkddpsqsanllaeakklndaqapk