PDB entry 4nos

View 4nos on RCSB PDB site
Description: human inducible nitric oxide synthase with inhibitor
Class: Oxidoreductase
Keywords: L-ARGININE MONOOXYGENASE, NITRIC OXIDE, HUMAN, ZNS4, Oxidoreductase
Deposited on 1999-02-03, released 2000-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.199
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inducible nitric oxide synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35228
      • conflict (341)
    Domains in SCOPe 2.08: d4nosa_
  • Chain 'B':
    Compound: inducible nitric oxide synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35228
      • conflict (341)
    Domains in SCOPe 2.08: d4nosb_
  • Chain 'C':
    Compound: inducible nitric oxide synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35228
      • conflict (341)
    Domains in SCOPe 2.08: d4nosc_
  • Chain 'D':
    Compound: inducible nitric oxide synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35228
      • conflict (341)
    Domains in SCOPe 2.08: d4nosd_
  • Heterogens: ZN, HEM, H2B, ITU, H4B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nosA (A:)
prhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellp
qaiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprci
griqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwn
aqliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfei
ppdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvr
dfcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaae
sfmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvw
qdekrrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4nosA (A:)
rhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellpq
aiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprcig
riqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwna
qliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfeip
pdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvrd
fcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaaes
fmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvwq
d

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nosB (B:)
prhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellp
qaiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprci
griqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwn
aqliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfei
ppdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvr
dfcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaae
sfmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvw
qdekrrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4nosB (B:)
rhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellpq
aiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprcig
riqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwna
qliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfeip
pdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvrd
fcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaaes
fmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvwq
d

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4nosC (C:)
prhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellp
qaiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprci
griqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwn
aqliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfei
ppdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvr
dfcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaae
sfmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvw
qdekrrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4nosC (C:)
rhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellpq
aiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprcig
riqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwna
qliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfeip
pdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvrd
fcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaaes
fmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvwq
d

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4nosD (D:)
prhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellp
qaiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprci
griqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwn
aqliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfei
ppdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvr
dfcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaae
sfmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvw
qdekrrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4nosD (D:)
rhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkptppdellpq
aiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprcig
riqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwna
qliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfeip
pdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvrd
fcdvqrynileevgrrmglethklaslwkdqavveiniavihsfqkqnvtimdhhsaaes
fmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvwq
d