PDB entry 4nn6

View 4nn6 on RCSB PDB site
Description: cytokine receptor complex - crystal form 1b
Deposited on 2013-11-16, released 2014-03-19
The last revision was dated 2018-03-07, with a file datestamp of 2018-03-02.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymic stromal lymphopoietin
    Species: Mus musculus [TaxId:10090]
    Gene: Tslp
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JIE6
      • engineered mutation (103)
  • Chain 'B':
    Compound: Interleukin-7 receptor subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: Il7r, IL7RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Cytokine receptor-like factor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Crlf2, CRLF2 (TSLPR), Crlm2, Tpte2, Tslpr
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CII9
      • engineered mutation (102)
      • conflict (159)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4nn6A (A:)
ynfsncnftsitkiycniifhdltgdlkgakfeqiedceskpacllkieyytlnpipgcp
slpdktfarrtrealndhcpgypeterndgtqemaqevqniclqqtsqilrlwysfmqsp
egtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >4nn6A (A:)
fsncnftsitkiycniifhdltgdlkgakfeqiedceskpacllkieyytlnpipgcpsl
pdktfarrtrealndhcpvqniclqqtsqilrlwysfmqsp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4nn6B (B:)
gshmesgnaqdgdledadaddhsfwchsqlevdgsqhlltcafndsdintanlefqicga
llrvkcltlnklqdiyfiktseflligssnicvklgqknltcknmaintivkaeapsdlk
vvyrkeandflvtfnaphlkkkylkkvkhdvayrpargesnwthvslfhtrttipqrklr
pkamyeikvrsiphndyfkgfwsewspsstfetpepknqggwd

    Sequence, based on observed residues (ATOM records):
    >4nn6B (B:)
dhsfwchsqlevdgsqhlltcafnintanlefqicgallrvkcltlnklqdiyfiktsef
lligssnicvklgqknltcknmaintivkaeapsdlkvvyrkeandflvtfnaphlkkky
lkkvkhdvayrpargesnwthvslfhtrttipqrklrpkamyeikvrsiphndyfkgfws
ewspsstfetpep

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4nn6C (C:)
aaavtsrgdvtvvchdletvevtwgsgpdhhganlslefrygtgalqpcpryflsgagvt
sgcilpaaragllelalrdgggamvfkarqrasawlkprppwqvtllwtpdgdvtvswpa
hsylgldyevqhresnddedawqttsgpccdltvggldpvrcydfrvraspraahyglea
qpsewtavtrlsgaasaasctasgtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >4nn6C (C:)
tvvchdletvevtwlslefrygtgalqpcpryflsgtsgcilpaaragllelalmvfkar
qrasawlkprppwqvtllwtpdgdvtvswpahsylgldyevqhresnddedawqttsgpc
cdltvggldpvrcydfrvraspraahygleaqpsewtavtrls