PDB entry 4nm5
View 4nm5 on RCSB PDB site
Description: Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 c-motif
Class: transferase/peptide
Keywords: Wnt, LRP6, Auto-inhibited, GSK-3, Axin, kinase, primed substrate, phosphorylated Wnt receptor LRP6 c-motif, TRANSFERASE-PEPTIDE complex
Deposited on
2013-11-14, released
2014-03-26
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-03-26, with a file datestamp of
2014-03-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.185
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GSK3B protein
Species: Homo sapiens [TaxId:9606]
Gene: GSK3B, hCG_1818062
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4nm5a_ - Chain 'B':
Compound: Axin-1
Species: Homo sapiens [TaxId:9606]
Gene: AXIN1, AXIN
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: Phosphorylated Wnt receptor LRP6 c-motif
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: ADP, GOL, MG, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4nm5A (A:)
sckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyq
aklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvl
dyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpd
tavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelll
gqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppe
aialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpp
latilippharhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4nm5A (A:)
gsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelva
ikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrva
rhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgs
akqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgv
dqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlley
tptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar
h
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.