PDB entry 4nkg

View 4nkg on RCSB PDB site
Description: Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain
Class: Ligase/Transferase
Keywords: LEUCINE-RICH REPEAT, COILED-COIL, E3 ligase substrate interaction, Ligase-Transferase complex
Deposited on 2013-11-12, released 2013-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-01-22, with a file datestamp of 2014-01-17.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.21
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase sspH1
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:588858]
    Gene: sspH1, STM14_1483
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Serine/threonine-protein kinase N1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1, PKN, PKN1, PRK1, PRKCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nkgb_
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase sspH1
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:588858]
    Gene: sspH1, STM14_1483
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0ZVG2 (1-End)
      • expression tag (0)
  • Chain 'D':
    Compound: Serine/threonine-protein kinase N1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1, PKN, PKN1, PRK1, PRKCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nkgd_
  • Heterogens: HEZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nkgB (B:)
gamdatnlsrvaglekqlaielkvkqgaenmiqtysngstkdrkllltaqqmlqdsktki
diirmqlrralqagqlenqaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4nkgB (B:)
lsrvaglekqlaielkvkqgaenmiqtysngstkdrkllltaqqmlqdsktkidiirmql
rralqa

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4nkgD (D:)
gamdatnlsrvaglekqlaielkvkqgaenmiqtysngstkdrkllltaqqmlqdsktki
diirmqlrralqagqlenqaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4nkgD (D:)
lsrvaglekqlaielkvkqgaenmiqtysngstkdrkllltaqqmlqdsktkidiirmql
rralq