PDB entry 4nii
View 4nii on RCSB PDB site
Description: Crystal structure of AlkB D135I mutant protein with cofactors bound to dsDNA containing m6A/A
Class: oxidoreductase/DNA
Keywords: DNA/RNA direct repair, jelly-roll fold, DNA/RNA demethylation repair, Fe(II), 2-KG, OXIDOREDUCTASE-DNA complex
Deposited on
2013-11-06, released
2014-04-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-05-28, with a file datestamp of
2014-05-23.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: 0.176
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Alpha-ketoglutarate-dependent dioxygenase AlkB
Species: Escherichia coli [TaxId:562]
Gene: alkB, aidD, b2212, JW2200
Database cross-references and differences (RAF-indexed):
- Uniprot P05050 (0-End)
- engineered mutation (117)
- engineered mutation (123)
Domains in SCOPe 2.08: d4niia_ - Chain 'B':
Compound: 5'-d(*tp*ap*gp*gp*tp*ap*ap*(6ma)p*ap*cp*cp*gp*t)-3'
- Chain 'C':
Compound: 5'-d(*ap*ap*cp*gp*gp*tp*ap*tp*tp*ap*cp*cp*t)-3'
- Heterogens: MN, AKG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4niiA (A:)
qeplaagavilrrfafnaaeqlirdindvasqspfrqmvtpggytmsvamtncghlgwtt
hrqgylyspidpqtnkpwpampqsfhnlcqraataagypdfqpdaclinryapgaklclh
qdkiepdlrapivsvslglpaifqfgglkrndplkrlllehgdvvvwggesrlfyhgiqp
lkagfhpltidcrynltfrqagkke
Sequence, based on observed residues (ATOM records): (download)
>4niiA (A:)
qeplaagavilrrfafnaaeqlirdindvasqspfrqmvtpggytmsvamtncghlgwtt
hrqgylyspidpqtnkpwpampqsfhnlcqraataagypdfqpdaclinryapgaklclh
qdkilrapivsvslglpaifqfgglkrndplkrlllehgdvvvwggesrlfyhgiqplka
gfhpltidcrynltfrqagk
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.