PDB entry 4nhd

View 4nhd on RCSB PDB site
Description: Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A
Class: transferase
Keywords: STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, Vibrio cholerae, beta-ketoacyl-(acyl carrier protein) synthase III, TRANSFERASE
Deposited on 2013-11-04, released 2013-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1
    Species: Vibrio cholerae O1 biovar El Tor [TaxId:243277]
    Gene: fabH1, VC2023, VC_2023
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH5 (3-318)
      • expression tag (2)
    Domains in SCOPe 2.08: d4nhda1, d4nhda2, d4nhda3
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1
    Species: Vibrio cholerae O1 biovar El Tor [TaxId:243277]
    Gene: fabH1, VC2023, VC_2023
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH5 (3-318)
      • expression tag (2)
    Domains in SCOPe 2.08: d4nhdb1, d4nhdb2, d4nhdb3
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1
    Species: Vibrio cholerae O1 biovar El Tor [TaxId:243277]
    Gene: fabH1, VC2023, VC_2023
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH5 (3-318)
      • expression tag (2)
    Domains in SCOPe 2.08: d4nhdc1, d4nhdc2, d4nhdc3
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1
    Species: Vibrio cholerae O1 biovar El Tor [TaxId:243277]
    Gene: fabH1, VC2023, VC_2023
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KQH5 (3-318)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d4nhdd1, d4nhdd2, d4nhdd3
  • Heterogens: COA, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nhdA (A:)
snamyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaff
aaqnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmy
alsiadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilst
hihadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhksel
dwlvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqm
llleafgggftwgsalvkf

    Sequence, based on observed residues (ATOM records): (download) 
    >4nhdA (A:)
amyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaffaa
qnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmyal
siadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilsthi
hadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhkseldw
lvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqmll
leafgggftwgsalvkf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nhdB (B:)
snamyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaff
aaqnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmy
alsiadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilst
hihadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhksel
dwlvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqm
llleafgggftwgsalvkf

    Sequence, based on observed residues (ATOM records): (download) 
    >4nhdB (B:)
amyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaffaa
qnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmyal
siadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilsthi
hadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhkseldw
lvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqmll
leafgggftwgsalvkf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4nhdC (C:)
snamyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaff
aaqnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmy
alsiadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilst
hihadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhksel
dwlvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqm
llleafgggftwgsalvkf

    Sequence, based on observed residues (ATOM records): (download) 
    >4nhdC (C:)
amyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaffaa
qnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmyal
siadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilsthi
hadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhkseldw
lvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqmll
leafgggftwgsalvkf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4nhdD (D:)
snamyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaff
aaqnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmy
alsiadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilst
hihadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhksel
dwlvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqm
llleafgggftwgsalvkf

    Sequence, based on observed residues (ATOM records): (download) 
    >4nhdD (D:)
namyskilgtgsylpsqvrtnadlekmvetsdewivartgirerriaadnetvadmaffa
aqnainmagidkhdidmiivattsashtfpsaacqvqgklgikgcpafdlaaacsgfmya
lsiadqhvksgmckhvlvigadalsktcdptdrstiilfgdgagavvvgasnepgilsth
ihadgefgdllslevpvrggdsdkwlhmagnevfkvavtqlsklvvdtlkannmhkseld
wlvphqanyriisatakklsmsldqvvitldrhgntsaatvptaldeavrdgriqrgqml
lleafgggftwgsalvkf