PDB entry 4ngg

View 4ngg on RCSB PDB site
Description: structure of human dicer platform-paz-connector helix cassette in complex with 13-mer sirna having 5'-a and uu-3' ends (2.6 angstrom resolution)
Deposited on 2013-11-01, released 2014-03-05
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endoribonuclease Dicer
    Species: Homo sapiens [TaxId:9606]
    Gene: DICER, DICER1, HERNA, KIAA0928
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UPY3
      • engineered mutation (68-69)
  • Chain 'B':
    Compound: 5'-r(*ap*gp*cp*gp*ap*ap*up*up*cp*gp*cp*up*u)-3'
  • Heterogens: PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4nggA (A:)
sdqpcylyvigmvlttplpdelnfrrrklyppedttrcfgiltakpipqiphfpvytrsg
evtisielaasgfmlslqmlelitrlhqyifshilrlekpalefkptdadsaycvlplnv
vndsstldidfkfmedieksearigipstkytketpfvfkledyqdaviipryrnfdqph
rfyvadvytdltplskfpspeyetfaeyyktkynldltnlnqplldvdhtssrlnlltpr
hlnqkgkalplssaekrkakweslqnkqilvpelcaihpipaslwrkavclpsilyrlhc
ll

    Sequence, based on observed residues (ATOM records):
    >4nggA (A:)
qpcylyvigmvlttplpdelnfrrrklyppedttrcfgiltakpipqiphfpvytrsgev
tisielaasgfmlslqmlelitrlhqyifshilrleycvlplnvvndstldidfkfmedi
eksearigipstkytketpfvfkledyqdaviipryrnfdqphrfyvadvytdltplskf
pspeyetfaeyyktkynldltnlnqplldvdhtssrlnlltprrkakweslqnkqilvpe
lcaihpipaslwrkavclpsilyrlhc

  • Chain 'B':
    No sequence available.