PDB entry 4ngb

View 4ngb on RCSB PDB site
Description: structure of human dicer platform-paz-connector helix cassette in complex with 12-mer sirna having uu-3' ends (2.25 angstrom resolution)
Deposited on 2013-11-01, released 2014-03-05
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endoribonuclease Dicer
    Species: Homo sapiens [TaxId:9606]
    Gene: DICER, DICER1, HERNA, KIAA0928
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UPY3
      • engineered mutation (68-69)
  • Chain 'B':
    Compound: 5'-r(*gp*cp*gp*ap*ap*up*up*cp*gp*cp*up*u)-3'
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4ngbA (A:)
sdqpcylyvigmvlttplpdelnfrrrklyppedttrcfgiltakpipqiphfpvytrsg
evtisielaasgfmlslqmlelitrlhqyifshilrlekpalefkptdadsaycvlplnv
vndsstldidfkfmedieksearigipstkytketpfvfkledyqdaviipryrnfdqph
rfyvadvytdltplskfpspeyetfaeyyktkynldltnlnqplldvdhtssrlnlltpr
hlnqkgkalplssaekrkakweslqnkqilvpelcaihpipaslwrkavclpsilyrlhc
ll

    Sequence, based on observed residues (ATOM records):
    >4ngbA (A:)
qpcylyvigmvlttplpdelnfrrrklyppedttrcfgiltakpipqiphfpvytrsgev
tisielaasgfmlslqmlelitrlhqyifshilrlekpalaycvlplnvvsstldidfkf
medieksearigipstkytketpfvfkledyqdaviipryrnfdqphrfyvadvytdltp
lskfpspeyetfaeyyktkynldltnlnqplldvdhtssrlnlltplssaekrkakwesl
qnkqilvpelcaihpipaslwrkavclpsilyrlhc

  • Chain 'B':
    No sequence available.