PDB entry 4nfs

View 4nfs on RCSB PDB site
Description: V203A horse liver alcohol dehydrogenase E complexed with NAD and 2,2,2-trifluoroethanol
Class: oxidoreductase
Keywords: Rossmann fold, dehydrogenase, NAD, liver cytosol, oxidoreductase
Deposited on 2013-10-31, released 2013-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alcohol dehydrogenase e chain
    Species: Equus caballus [TaxId:9796]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00327 (0-373)
      • engineered mutation (202)
    Domains in SCOPe 2.08: d4nfsa1, d4nfsa2
  • Chain 'B':
    Compound: alcohol dehydrogenase e chain
    Species: Equus caballus [TaxId:9796]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00327 (0-373)
      • engineered mutation (202)
    Domains in SCOPe 2.08: d4nfsb1, d4nfsb2
  • Heterogens: ZN, NAJ, ETF, MRD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4nfsA (A:)
stagkvikckaavlweekkpfsieevevappkahevrikmvatgicrsddhvvsgtlvtp
lpviagheaagivesigegvttvrpgdkviplftpqcgkcrvckhpegnfclkndlsmpr
gtmqdgtsrftcrgkpihhflgtstfsqytvvdeisvakidaasplekvcligcgfstgy
gsavkvakvtqgstcavfglggaglsvimgckaagaariigvdinkdkfakakevgatec
vnpqdykkpiqevltemsnggvdfsfevigrldtmvtalsccqeaygvsvivgvppdsqn
lsmnpmlllsgrtwkgaifggfkskdsvpklvadfmakkfaldplithvlpfekinegfd
llrsgesirtiltf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4nfsB (B:)
stagkvikckaavlweekkpfsieevevappkahevrikmvatgicrsddhvvsgtlvtp
lpviagheaagivesigegvttvrpgdkviplftpqcgkcrvckhpegnfclkndlsmpr
gtmqdgtsrftcrgkpihhflgtstfsqytvvdeisvakidaasplekvcligcgfstgy
gsavkvakvtqgstcavfglggaglsvimgckaagaariigvdinkdkfakakevgatec
vnpqdykkpiqevltemsnggvdfsfevigrldtmvtalsccqeaygvsvivgvppdsqn
lsmnpmlllsgrtwkgaifggfkskdsvpklvadfmakkfaldplithvlpfekinegfd
llrsgesirtiltf