PDB entry 4nfn

View 4nfn on RCSB PDB site
Description: Human tau tubulin kinase 1 (TTBK1) complexed with 3-({5-[(4-amino-4-methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-bromophenol
Class: transferase/transferase inhibitor
Keywords: protein kinase, phosphotransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-10-31, released 2014-02-05
The last revision prior to the SCOPe 2.03 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: 0.186
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tau-tubulin kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TTBK1, BDTK, KIAA1855
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4nfna_
  • Heterogens: 2KC, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nfnA (A:)
ghmsgggeqadilpanyvvkdrwkvlkkiggggfgeiyeamdlltrenvalkvesaqqpk
qvlkmevavlkklqgkdhvcrfigcgrnekfnyvvmqlqgrnladlrrsqprgtftlstt
lrlgkqilesieaihsvgflhrdikpsnfamgrlpstyrkcymldfglarqytnttgdvr
pprnvagfrgtvryasvnahknremgrhddlwslfymlvefavgqlpwrkikdkeqvgmi
kekyehrmllkhmpsefhlfldhiasldyftkpdyqlimsvfensmkergiaeneafdwe
kagtdalls

    Sequence, based on observed residues (ATOM records): (download) 
    >4nfnA (A:)
dilpanyvvkdrwkvlkkiggggfgeiyeamdlltrenvalkvesaqqpkqvlkmevavl
kklqgkdhvcrfigcgrnekfnyvvmqlqgrnladlrrsqprgtftlsttlrlgkqiles
ieaihsvgflhrdikpsnfamgrlpstyrkcymldfglarqytnttgdvrpprnvagfrg
tvryasvnahknremgrhddlwslfymlvefavgqlpwrkikdkeqvgmikekyehrmll
khmpsefhlfldhiasldyftkpdyqlimsvfensmkergiaeneafdwekag