PDB entry 4neh

View 4neh on RCSB PDB site
Description: an internal ligand-bound, metastable state of a leukocyte integrin, axb2
Deposited on 2013-10-29, released 2014-01-15
The last revision was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin alpha-X
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGAX, CD11C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20702 (0-1081)
      • conflict (41)
      • conflict (367)
      • conflict (677)
      • conflict (884)
      • conflict (919)
      • expression tag (1082-1083)
  • Chain 'B':
    Compound: Integrin beta-2
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGB2, CD18, MFI7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05107 (0-673)
      • conflict (189)
      • conflict (231)
      • conflict (673)
      • expression tag (674-675)
  • Heterogens: CA, MG, NAG, CL, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4nehA (A:)
fnldteeltafrvdsagfgdsvvqyanswvvvgapqkitaadqtgglyqcgystgacepi
glqvppeavnmslglslasttspsqllacgptvhhecgrnmyltglcfllgptqltqrlp
vsrqecprqeqdivflidgsgsissrnfatmmnfvravisqfqrpstqfslmqfsnkfqt
hftfeefrrssnplsllasvhqlqgftytataiqnvvhrlfhasygarrdaakilivitd
gkkegdsldykdvipmadaagiiryaigvglafqnrnswkelndiaskpsqehifkvedf
dalkdiqnqlkekifaiegtettssssfelemaqegfsavftpdgpvlgavgsftwsgga
flyppnmdptfinmsqenvdmrdsylgystelalwkgvqslvlgapryqhtgkaviftqv
srqwrmkaevtgtqigsyfgaslcsvdvdsdgstdlvligaphyyeqtrggqvsvcplpr
gwrrwwcdavlygeqghpwgrfgaaltvlgdvngdkltdvvigapgeeenrgavylfhgv
lgpsispshsqriagsqlssrlqyfgqalsggqdltqdglvdlavgargqvlllrtrpvl
wvgvsmqfipaeiprsafecreqvvseqtlvqsniclyidkrsknllgsrdlqssvtldl
aldpgrlspratfqetktrslsrvrvlglkahcenfnlllpscvedsvtpitlrlnftlv
gkpllafrnlrpmlaadaqryftaslpfekncgadhicqdnlgisfsfpglksllvgsnl
elnaevmvwndgedsygttitfshpaglsyryvaegqkqgqlrslhltcdsapvgsqgtw
stscrinhlifrggaqitflatfdvspkavlgdrllltanvssesntprtskttfqlelp
vkyavytvvssheqftkylcfseseekeshvamhryqvnnlgqrdlpvsinfwvpvelnq
eavwmdvevshpqnpslrcssekiappasdflahiqknpvldcsiagclrfrcdvpsfsv
qeeldftlkgnlsfgwvrqilqkkvsvvsvaeitfdtsvysqlpgqeafmraqtttvlek
ykpgpaalqtlfqg

    Sequence, based on observed residues (ATOM records):
    >4nehA (A:)
fnldteeltafrvdsagfgdsvvqyanswvvvgapqkitaadqtgglyqcgystgacepi
glqvppeavnmslglslasttspsqllacgptvhhecgrnmyltglcfllgptqltqrlp
vsrqecprqeqdivflidgsgsissrnfatmmnfvravisqfqrpstqfslmqfsnkfqt
hftfeefrrssnplsllasvhqlqgftytataiqnvvhrlfhasygarrdaakilivitd
gkkegdsldykdvipmadaagiiryaigvglafqnrnswkelndiaskpsqehifkvedf
dalkdiqnqlkekifaiegtettssssfelemaqegfsavftpdgpvlgavgsftwsgga
flyppnmdptfinmsqenvdmrdsylgystelalwkgvqslvlgapryqhtgkaviftqv
srqwrmkaevtgtqigsyfgaslcsvdvdsdgstdlvligaphyyeqtrggqvsvcplpr
gwrrwwcdavlygeqghpwgrfgaaltvlgdvngdkltdvvigapgeeenrgavylfhgv
lgpsispshsqriagsqlssrlqyfgqalsggqdltqdglvdlavgargqvlllrtrpvl
wvgvsmqfipaeiprsafecreqvvseqtlvqsniclyidkrsknllgsrdlqssvtldl
aldpgrlspratfqetktrslsrvrvlglkahcenfnlllpscvedsvtpitlrlnftlv
gkpllafrnlrpmlaadaqryftaslpfekncgadhicqdnlgisfsfpglksllvgsnl
elnaevmvwndgedsygttitfshpaglsyryvaegqkqgqlrslhltcdsapvgsqgtw
stscrinhlifrggaqitflatfdvspkavlgdrllltanvssesntprtskttfqlelp
vkyavytvvssheqftkylcfseseekeshvamhryqvnnlgqrdlpvsinfwvpvelnq
eavwmdvevshpqnpslrcssekiappasdflahiqknpvldcsiagclrfrcdvpsfsv
qeeldftlkgnlsfgwvrqilqkkvsvvsvaeitfdtsvysqlpgqeafmraqtttvlek
ykpg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4nehB (B:)
qectkfkvsscreciesgpgctwcqklnftgpgdpdsircdtrpqllmrgcaaddimdpt
slaetqedhnggqkqlspqkvtlylrpgqaaafnvtfrrakgypidlyylmdlsysmldd
lrnvkklggdllralneitesgrigfgsfvdktvlpfvnthpdklrnpcpnkekecqppf
afrhvlkltdnsnqfqtevgkqlisgnldapeggldammqvaacpeeigwrkvtrllvfa
tddgfhfagdgklgailtpndgrchlednlykrsnefdypsvgqlahklaenniqpifav
tsrmvktyeklteiipksavgelsedssnvvqliknaynklssrvfldhnalpdtlkvty
dsfcsngvthrnqprgdcdgvqinvpitfqvkvtateciqeqsfviralgftdivtvqvl
pqcecrcrdqsrdrslchgkgflecgicrcdtgyigkncecqtqgrssqelegscrkdnn
siicsglgdcvcgqclchtsdvpgkliygqycecdtinceryngqvcggpgrglcfcgkc
rchpgfegsacqcerttegclnprrvecsgrgrcrcnvcechsgyqlplcqecpgcpspc
gkyiscaeclkfekgpfgkncsaacpglqlsnnpvkgrtckerdsegcwvaytleqqdgm
dryliyvdesreccggpaalqtlfqg

    Sequence, based on observed residues (ATOM records):
    >4nehB (B:)
qectkfkvsscreciesgpgctwcqklnftgpgdpdsircdtrpqllmrgcaaddimdpt
slaetqedqkqlspqkvtlylrpgqaaafnvtfrrakgypidlyylmdlsysmlddlrnv
kklggdllralneitesgrigfgsfvdktvlpfvnthpdklrnpcpnkekecqppfafrh
vlkltdnsnqfqtevgkqlisgnldapeggldammqvaacpeeigwrkvtrllvfatddg
fhfagdgklgailtpndgrchlednlykrsnefdypsvgqlahklaenniqpifavtsrm
vktyeklteiipksavgelsedssnvvqliknaynklssrvfldhnalpdtlkvtydsfc
sngvthrnqprgdcdgvqinvpitfqvkvtateciqeqsfviralgftdivtvqvlpqce
crcrdrslchgkgflecgicrcdtgyigkncecqtqgrssqelegscrkdnnsiicsglg
dcvcgqclchtsdvpgkliygqycecdtinceryngqvcggpgrglcfcgkcrchpgfeg
sacqcerttegclnprrvecsgrgrcrcnvcechsgyqlplcqecpgcpspcgkyiscae
clkfekgpfgkncsaacpglqlsnnpvkgrtckerdsegcwvaytleqqdgmdryliyvd
esreccgg