PDB entry 4ncr

View 4ncr on RCSB PDB site
Description: Crystal structure of M. tuberculosis DprE1 in complex with PBTZ169
Deposited on 2013-10-25, released 2014-02-19
The last revision was dated 2014-04-02, with a file datestamp of 2014-03-28.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: 0.19
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: decaprenylphosphoryl-beta-D-ribose oxidase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: dprE1, MT3898, Rv3790
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: decaprenylphosphoryl-beta-D-ribose oxidase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: dprE1, MT3898, Rv3790
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 26J, FAD, GOL, IMD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4ncrA (A:)
mgsshhhhhhssglvprgshmlsvgatttatrltgwgrtapsvanvlrtpdaemivkava
rvaesgggrgaiarglgrsygdnaqnggglvidmtplntihsidadtklvdidagvnldq
lmkaalpfglwvpvlpgtrqvtvggaiacdihgknhhsagsfgnhvrsmdlltadgeirh
ltptgedaelfwatvggngltgiimratiemtptstayfiadgdvtasldetialhsdgs
earytyssawfdaisappklgraavsrgrlatveqlpaklrseplkfdapqlltlpdvfp
nglankytfgpigelwyrksgtyrgkvqnltqfyhpldmfgewnraygpagflqyqfvip
teavdefkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfv
seldrrvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlel
l

    Sequence, based on observed residues (ATOM records):
    >4ncrA (A:)
atttatrltgwgrtapsvanvlrtpdaemivkavarvaesgggrgaiarglgrsygdnaq
nggglvidmtplntihsidadtklvdidagvnldqlmkaalpfglwvpvlpgtrqvtvgg
aiacdihgknhhsagsfgnhvrsmdlltadgeirhltptgedaelfwatvggngltgiim
ratiemtptstayfiadgdvtasldetialhsdgsearytyssawfdaisappklgraav
srgrlatveqlpaklrseplkfdapqankytfgpigelwyrksgtyrgkvqnltqfygfl
qyqfvipteavdefkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpik
dglgkfvseldrrvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasd
marrlell

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4ncrB (B:)
mgsshhhhhhssglvprgshmlsvgatttatrltgwgrtapsvanvlrtpdaemivkava
rvaesgggrgaiarglgrsygdnaqnggglvidmtplntihsidadtklvdidagvnldq
lmkaalpfglwvpvlpgtrqvtvggaiacdihgknhhsagsfgnhvrsmdlltadgeirh
ltptgedaelfwatvggngltgiimratiemtptstayfiadgdvtasldetialhsdgs
earytyssawfdaisappklgraavsrgrlatveqlpaklrseplkfdapqlltlpdvfp
nglankytfgpigelwyrksgtyrgkvqnltqfyhpldmfgewnraygpagflqyqfvip
teavdefkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfv
seldrrvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlel
l

    Sequence, based on observed residues (ATOM records):
    >4ncrB (B:)
ttatrltgwgrtapsvanvlrtpdaemivkavarvaesgggrgaiarglgrsygdnaqng
gglvidmtplntihsidadtklvdidagvnldqlmkaalpfglwvpvlpgtrqvtvggai
acdihgknhhsagsfgnhvrsmdlltadgeirhltptgedaelfwatvggngltgiimra
tiemtptstayfiadgdvtasldetialhsdgsearytyssawfdaisappklgraavsr
grlatveqlpaklrseplkfdapwyrksgtyrgkvqnltqfygflqyqfvipteavdefk
kiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfvseldrrvl
efggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlell