PDB entry 4nca

View 4nca on RCSB PDB site
Description: structure of thermus thermophilus argonaute bound to guide dna 19-mer and target dna in the presence of mn2+
Deposited on 2013-10-24, released 2014-01-15
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Argonaute
    Species: Thermus thermophilus [TaxId:274]
    Gene: Argonaute, TT_P0026
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Argonaute
    Species: Thermus thermophilus [TaxId:274]
    Gene: Argonaute, TT_P0026
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 5'-d(p*tp*gp*ap*gp*gp*tp*ap*gp*tp*ap*gp*gp*tp*tp*gp*tp*ap*tp*ap*gp*t)-3'
  • Chain 'D':
    Compound: 5'-d(p*tp*ap*cp*tp*ap*cp*cp*tp*cp*g)-3'
  • Chain 'E':
    Compound: 5'-d(p*tp*gp*ap*gp*gp*tp*ap*gp*tp*ap*gp*gp*tp*tp*gp*tp*ap*tp*ap*gp*t)-3'
  • Chain 'F':
    Compound: 5'-d(p*tp*ap*cp*tp*ap*cp*cp*tp*cp*g)-3'
  • Chain 'G':
    Compound: 5'-d(*ap*cp*ap*ap*cp*c)-3'
  • Chain 'H':
    Compound: 5'-d(*ap*cp*ap*ap*cp*c)-3'
  • Heterogens: DT, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4ncaA (A:)
mnhlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrm
gdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqer
lrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsle
awlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggr
vawvadpkdprkpiphltgllvpvltledlheeegslalslpweerrrrtreiaswigrr
lglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpef
lrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnr
lkalllreglpsqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdag
gresfrfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsr
vlllrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledkt
fllltvhrdfrgtprplklvheagdtplealahqifhltrlypasgfafprlpaplhlad
rlvkevgrlgirhlkevdreklffv

    Sequence, based on observed residues (ATOM records):
    >4ncaA (A:)
hlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrmgd
glaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlr
rlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleaw
laqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrva
wvadpkdprkpiphltgllvpvltledlheeegslalslpweerrrrtreiaswigrrlg
lgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflr
rallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlk
alllreglpsqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdaggr
esfrfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvl
llrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfl
lltvhrdfrgtprplklvheagdtplealahqifhltrlypasgfafprlpaplhladrl
vkevgrlgirhlkevdreklffv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4ncaB (B:)
mnhlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrm
gdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqer
lrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsle
awlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggr
vawvadpkdprkpiphltgllvpvltledlheeegslalslpweerrrrtreiaswigrr
lglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpef
lrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnr
lkalllreglpsqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdag
gresfrfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsr
vlllrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledkt
fllltvhrdfrgtprplklvheagdtplealahqifhltrlypasgfafprlpaplhlad
rlvkevgrlgirhlkevdreklffv

    Sequence, based on observed residues (ATOM records):
    >4ncaB (B:)
lgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrmgdg
laswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrr
legvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawl
aqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggrvaw
vadpkkpiphltgllvpvltledlheegslalslpweerrrrtreiaswigrrlglgtpe
avraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallr
afgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllr
eglpsqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdaggresfrf
ggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrdg
rvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvh
rdfrgtprplklvheagdtplealahqifhltrlypasgfafprlpaplhladrlvkevg
rlgirhlkevdreklffv

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.