PDB entry 4na9

View 4na9 on RCSB PDB site
Description: Factor VIIa in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, hydrolase, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, glycoprotein, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-10-21, released 2014-02-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2014-02-12, with a file datestamp of 2014-02-07.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: 0.225
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Coagulation factor VII heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4na9h_
  • Chain 'L':
    Compound: Coagulation factor VII light chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4na9l_
  • Heterogens: 1T7, CA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4na9H (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4na9L (L:)
    icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr