PDB entry 4na9
View 4na9 on RCSB PDB site
Description: Factor VIIa in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, hydrolase, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, glycoprotein, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2013-10-21, released
2014-02-12
The last revision prior to the SCOPe 2.03 freeze date was dated
2014-02-12, with a file datestamp of
2014-02-07.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: 0.225
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Coagulation factor VII heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4na9h_ - Chain 'L':
Compound: Coagulation factor VII light chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4na9l_ - Heterogens: 1T7, CA, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>4na9H (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>4na9L (L:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr